Scalp Cooling to Prevent Hair Loss in Patients Undergoing Stem Cell Transplantation for Multiple Myeloma

What is the Purpose of this Study?

The purpose of this study is to determine whether a Penguin cold cap (used to reduce hair loss in patients with breast and ovarian cancers receiving chemotherapy) may also be effective at reducing hair loss in patients with multiple myeloma who are undergoing a stem cell transplant. Patients usually lose nearly all of their scalp hair after undergoing chemotherapy and stem cell transplantation for multiple myeloma. For many, the hair loss is upsetting and has kept some people from choosing to receive this potentially life-sustaining procedure. Melphalan is the chemotherapy drug used to kill the multiple myeloma cells prior to the stem cell transplantation. It kills cells that grow and replicate quickly (like hair cells). It is hoped that a cooling of the scalp will reduce injury to hair follicles. This may work because blood vessels in the skin constrict when cold, and this should reduce the amount of blood (and therefore melphalan within the blood) from getting to the hair follicles during the time of scalp cooling when the chemotherapy is in the body.


Eligibility

  • Age ≥18 years
  • ECOG performance status ≤2
  • Confirmed multiple myeloma diagnosis
  • Hair covering ≥75% of scalp on physical exam at screening visit
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Where can I participate?

Cedars-Sinai Cancer at SOCC : Amy Oppenheim

More about this Clinical Trial

What is the full name of this clinical trial?

IIT2023-03-Vescio-ColdCap: Scalp Cooling to Prevent Hair Loss in Patients Undergoing Stem Cell Transplantation for Multiple Myeloma

Study Details
Disease Type/Condition

Multiple Myeloma

Principal Investigator

Vescio, Robert

Co-Investigators

David Oveisi

Age Group

Adult

Phase

N/A (Cancer Control)

IRB Number

STUDY00002728

ClinicalTrials.gov ID

NCT05961215

Key Eligibility
ClinicalTrials.gov

How do I learn more about this study?
Name

Amy Oppenheim

Phone
+1 310-423-3713
Email
amy.oppenheim@cshs.org
Study Details
Disease Type/Condition

Multiple Myeloma

Principal Investigator

Vescio, Robert

Age Group

Adult

Phase

N/A (Cancer Control)

IRB Number

IIT2023-03-VESCIO-COLDCAP

ClinicalTrials.gov ID

NCT05961215

Key Eligibility
ClinicalTrials.gov

Contact
Name

Amy Oppenheim

Phone
+1 310-423-3713
Email
amy.oppenheim@cshs.org