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133 results found

Eye and Orbit, Liver, Melanoma

RP2 in Combination With Nivolumab Versus Ipilimumab in Combination With Nivolumab in Metastatic Uveal Melanoma

This study focuses on immune checkpoint inhibitor-naive adults with inoperable metastatic uveal melanoma (a type of aggressive eye cancer that has not been treated with immune checkpoint inhibitor therapies). The purpose of the study is ...

Esophagus, Stomach

Nivolumab + Paclitaxel + Ramucirumab in Advanced Gastric and Esophageal Adenocarcinoma

This study focuses on people who have advanced stomach or esophageal cancer that has spread. The purpose of the study is to compare the usual treatment alone (the combination of 2 drugs, paclitaxel and ramucirumab) ...

Ovary

Olaparib With or Without Bevacizumab in BRCA 1/2 Mutated or Homologous Recombination Deficient Ovarian Cancer

This study focuses on people with ovarian cancer who have tested positive for BRCA1/2 mutation (change or defect in the BRCA gene) or homologous recombination deficiency (when the body cannot repair breaks in DNA). The ...

Breast

Low-Dose Tamoxifen in Low-Risk, Early-Stage Breast Cancer

Hormone receptor-positive breast cancer is the most common type of breast cancer, and 5+ years of hormone therapy is the mainstay of the treatment. However, many patients experience side effects from the medications, and some ...

Lung

Amgen, 20230153, Ph 2, randomized, open-label, NSCLC, AMG193

Primary Objective: To characterize safety and efficacy of 2 dose levels of AMG 193 by investigator.