Find Clinical Trials | Cedars-Sinai

390 results found

Other

WATCHMAN FLX Pro Left Atrial Appendage Closure Device With Alternative Post-Implant Monotherapy

This study focuses on people who have a heart condition called atrial fibrillation (AFib). AFib can cause blood to pool in a part of the heart called the left atrial appendage, where blood clots can ...

Other

ION582 in Children and Adults with Angelman Syndrome

The purpose of this study is to determine the safety and effectiveness of an experimental drug called ION582 in children and adults with Angelman syndrome. Angelman syndrome is a rare genetic condition resulting in severe developmental ...

Breast

Bria-IMT Regimen With Check Point Inhibitor vs Physician’s Choice in Metastatic Breast Cancer

The purpose of this study is to assess the safety and effectiveness of an experimental therapy for advanced breast cancer called Bria-IMT (SV-BR-1-GM) cancer vaccine in combination with immune checkpoint inhibitor retifanlimab. Retifanlimab can help ...

Lung

BNT324 with BNT327 in Participants With Advanced Lung Cancer

The purpose of this study is to assess whether the investigational drugs BNT324 and BNT327 can help control advanced or metastatic lung cancer. The study aims to determine the most suitable combination dose of BNT324 ...

Unknown Sites

COG, AOST2032, Ph 2/3, randomized, osteosarcoma, Cabozantinib + Cytotoxic Chemo

Primary Aims 1.1.1 To determine the feasibility of adding cabozantinib to standard MAP (high dose methotrexate, doxorubicin, and cisplatin) chemotherapy in patients with newly diagnosed metastatic osteosarcoma with a resectable primary tumor. 1.1.2 To determine whether MAP ...