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322 results found


Non-Hodgkin's Lymphoma

Nivolumab With Chemo-Immunotherapy for the Treatment of Primary Mediastinal B-Cell Lymphoma

This study focuses on individuals who have been diagnosed with primary mediastinal B Cell lymphoma (PMBCL). PMBCL is a type of cancer that occurs in the upper chest (in an area called the mediastinum). The ...


Kidney

HC-7366 in Combination With Belzutifan in Renal Cell Carcinoma

The purpose of this study is to evaluate the safety and effectiveness of an experimental drug called HC-7366 in combination with another drug, belzutifan (also known as MK-6482) in people who have inoperable or metastatic ...


Brain and Nervous System, Breast, Cervix, Colon, Lung, Other Female ...

DF6215 in Advanced Solid Tumors

The purpose of this study is to determine the safety of an investigational drug called DF6215 in people who have a locally advanced or metastatic solid tumor. A locally advanced solid tumor is cancer that ...


Colon, Lung, Melanoma, Pancreas

Seagen, SGNBB228-001, Ph 1, Advanced Melanoma, Solid Tumors, SGN-BB228

Primary Objectives To evaluate the safety and tolerability of SGN-BB228 To identify the maximum tolerated dose (MTD) of SGN-BB228 (Part A) To identify a recommended dose and schedule for SGN-BB228 (Parts A ...


Multiple Myeloma

Alliance, A062102, Ph2, randomized, Multiple Myeloma, iberdomide vs observation

Primary Objective: To establish and confirm the safety and dose of iberdomide as maintenance after ide-cel CAR-T Secondary Objectives: Key secondary objective: To estimate the rate of conversion from MRD-positive at baseline to MRD-negative at any time ...