Find Clinical Trials | Cedars-Sinai

330 results found

Other

Mavacamten in Symptomatic Obstructive Hypertrophic Cardiomyopathy

This study focuses on people who have been diagnosed with obstructive hypertrophic cardiomyopathy (oHCM), a condition in which the heart muscle thickens and blocks blood flow from the heart. The purpose of the study is ...

Pancreas

RMC-6236 Versus Standard-of-Care Therapy in Previously Treated Metastatic Pancreatic Ductal Adenocarcinoma

The purpose of this study is to evaluate an experimental drug called RMC-6236 in pancreatic cancer patients whose cancer has spread outside the pancreas (metastatic) and whose cancer has returned after treatment or did not ...

Lymphoid Leukemia

AZ, D7405C00001, Ph I/II, Randomized, Rel or Refr B-Cell Acute Lymphoblastic Leukaemia, AZD0486

PART A - * Primary To assess the safety and tolerability of AZD0486 in participants with Ph(+) or Ph(-) R/R B-ALL, aged 16 to 80 years, inclusive *Secondary 1 To evaluate the preliminary efficacy of AZD0486 based on NCCN response ...

Breast, Kidney, Lung, Multiple Myeloma, Other Digestive Organ, Ovary, Pancreas ...

QXL138AM in Locally Advanced Unresectable and/or Metastatic Solid Tumors and Multiple Myeloma

The purpose of this study is to evaluate the safety and tolerability of an experimental drug called QXL138AM in people with advanced solid tumors and multiple myeloma. There are 2 parts to this study. In ...

Breast

AZ, D8535C00001, Ph 3, Rand, Breast cancer, AZD9833 vs SOC

Primary Objective: To demonstrate superiority of camizestrant ± abemaciclib as compared to standard ET ± abemaciclib by assessment of invasive breast cancer-free survival (IBCFS). Secondary Objectives: To demonstrate superiority of camizestrant ± abemaciclib as compared to standard ET ...