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VeraTherapeutics_VT-001-0060_Atacicept in Multiple Glomerular Diseases

Primary Objectives: 1) To evaluate the safety and tolerability of atacicept 2) To evaluate the effect of atacicept on change from baseline in proteinuria


Ovary

Ubamatamab in Platinum-Resistant Ovarian Cancer

The purpose of this study is to evaluate an investigational drug called ubamatamab in patients who have advanced ovarian cancer. Researchers want to determine how safe, tolerable, and effective ubamatamab is on its own and ...


Colon

Optimizing Body Weight With TCMCB07 in Patients With Newly Diagnosed Metastatic Colorectal Cancer Undergoing Chemotherapy

This study focuses on people with advanced colorectal cancer. The purpose of the study is to evaluate an experimental treatment called TCMB07 (B07) that may help cancer patients gain and/or maintain their weight while they ...


Unknown Sites

Verastem Oncology, VS-7375-101, Ph 1/2, Open, KRAS G12D-Mutant solid tumors, VS-7375

Primary Objective: Part A: VS-7375 Single Agent Dose Escalation To characterize the safety, tolerability, and AE profile of escalating doses of VS-7375 as 2L+ monotherapy administered on a daily oral schedule in participants with any KRAS ...


Unknown Sites

Zanzalintinib vs Everolimus in Locally Advanced or Metastatic Neuroendocrine Tumors

The purpose of this study is to evaluate the effectiveness of an experimental drug called zanzalintinib compared to the standard-of-care treatment, everolimus, in treating people with locally advanced or metastatic neuroendocrine tumors. Zanzalintinib is a ...