Find Clinical Trials | Cedars-Sinai

397 results found

Breast

Shortened Duration of Adjuvant Therapy in Early-Stage HER2+ Breast Cancer

This study focuses on people who have been diagnosed with HER2-positive (HER2+) breast cancer and have recently completed chemotherapy in combination with a drug called trastuzumab, followed by breast surgery. The chemotherapy plus trastuzumab produced ...

Unknown Sites

AVZO-1418 in Locally Advanced or Metastatic Solid Tumors

The purpose of this study is to evaluate the safety and tolerability of an experimental drug called AVZO-1418 for the treatment of locally advanced solid tumors (cancers that have grown to a serious stage and ...

Breast, Colon, Esophagus, Kidney, Liver, Lung, Melanoma, Other Female Genital ...

Corcept Therapeutics, CORT125236-750, Ph 1b/2, Nenocorilant in Combo w Nivo, Adv Solid Malignancies

Dose-Finding Phase 1b - Part 1 Primary Objectives: To evaluate the safety and tolerability of nenocorilant in combination with nivolumab in patients with advanced solid malignancies. To determine the maximum tolerated dose (MTD) and/or the ...

Colon, Rectum

Summit Therapeutics, SMT112-3005, Ph3, rand, Ivonescimab+FOLFOX vs Bev+FOLFOX, CRC

Primary Objective: To compare the progression-free survival (PFS) as assessed by blinded Independent Radiological Review Committee (IRRC) based on Response Evaluation Criteria in Solid Tumors (RECIST) v1.1, of ivonescimab in combination with modified 5-FU, oxaliplatin, and leucovorin (mFOLFOX6) ...

Lung

Shanghai Henlius Biotech, HLX43-NSCLC201, Ph II, Open, NSCLC, HLX43

Primary Objective: 1. To evaluate the clinical efficacy of HLX43 in advanced non-small cell lung cancer (NSCLC) Secondary Objectives: 1. To evaluate the safety and tolerability of HLX43 in patients with advanced NSCLC 2. To evaluate the pharmacokinetic (PK) characteristics and immunogenicity ...