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4 results found

✔ Disease Type/Condition: ATTR-CM

ATTR-CM, Cardiac Amyloidosis

Cardiac Amyloidosis: Strategy to Improve Patient Outcomes by Silencing TTR Formation in ATTR-CM (TTRansform)

- To evaluate the effect of treatment with ION-682884 compared to placebo for 120 weeks on the composite endpoint of cardiovascular (CV) mortality and frequency of CV clinical events in patients with ATTR-CM receiving available ...


ATTR-CM, Cardiac Amyloidosis

ATTR CM: Efficacy and Safety of NNC6019-0001 in Transthyretin Amyloid Cardiomyopathy (ATTR CM)

The purpose of this study is to determine whether an investigational drug called NNC6019-0001 can be used to treat people with transthyretin (TTR) amyloid cardiomyopathy, a heart disease due to TTR amyloidosis. Participants will undergo ...


ATTR-CM, Cardiac Amyloidosis

ATTR CM: Expanded access protocol to provide patisiran in patients with ATTR amyloidosis with cardiomyopathy (APOLLO EAP)

The objective of the study is to assess the long-term safety of patisiran in patients with ATTR amyloidosis with cardiomyopathy as assessed by a review of adverse events (AEs).


ATTR-CM

AG10-304

The purpose of this study is to evaluate the safety and effectiveness of an investigational drug called acoramidis (AG10) for the treatment of a rare disease called symptomatic transthyretin amyloid cardiomyopathy (ATTR-CM). ATTR-CM occurs when ...