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4 results found

ATTR-CM, Cardiac Amyloidosis

Cardiac Amyloidosis: Strategy to Improve Patient Outcomes by Silencing TTR Formation in ATTR-CM (TTRansform)

- To evaluate the effect of treatment with ION-682884 compared to placebo for 120 weeks on the composite endpoint of cardiovascular (CV) mortality and frequency of CV clinical events in patients with ATTR-CM receiving available ...

ATTR-CM, Cardiac Amyloidosis

AG10-304

The purpose of this study is to evaluate the safety and effectiveness of an investigational drug called acoramidis (AG10) for the treatment of a rare disease called symptomatic transthyretin amyloid cardiomyopathy (ATTR-CM). ATTR-CM occurs when ...

ATTR-CM, Cardiac Amyloidosis

ATTR CM: Efficacy and Safety of NNC6019-0001 in Transthyretin Amyloid Cardiomyopathy (ATTR CM)

The purpose of this study is to determine whether an investigational drug called NNC6019-0001 can be used to treat people with transthyretin (TTR) amyloid cardiomyopathy, a heart disease due to TTR amyloidosis. Participants will undergo ...

ATTR-CM, Cardiac Amyloidosis

ATTR Amyloidosis With Cardiomyopathy: Expanded Access Protocol to Provide Patisiran

This study is an Expanded Access Program that focuses on individuals who have transthyretin amyloidosis with cardiomyopathy (ATTR amyloidosis with cardiomyopathy). Expanded Access Programs are a means by which investigational treatments are made available to ...