Find Clinical Trials | Cedars-Sinai

141 results found

Brain and Nervous System

Carboplatin and Vincristine Versus Selumetinib in Low-Grade Glioma

This study focuses on individuals who have been diagnosed with a cancer called low-grade glioma (LGG). The purpose of the study is to determine whether an experimental drug called selumetinib is as effective as the ...

Brain and Nervous System

Primary CNS Lymphoma: Phase I Trial of Methotrexate, Rituximab, Lenalidomide, and Nivolumab

The purpose of this study is to determine whether the drugs rituximab, methotrexate, lenalidomide, and nivolumab can be safely combined for treatment of primary CNS lymphoma. Researchers also want to learn which dose is the ...

Melanoma

Melanoma Margins Trial: 1cm v 2cm Wide Excision Margins for Primary Cutaneous Melanoma

This study focuses on individuals who have been diagnosed with a form of skin cancer called melanoma, which develops from melanocytes (pigment cells). During surgery for melanoma, the skin cancer and a small margin of ...

Lung

Trastuzumab Deruxtecan in Non-Small Cell Lung Cancer

This study focuses on individuals who have unresectable, locally advanced or metastatic lung cancer with a mutation on the human epidermal growth factor receptor 2 (HER2). HER2 is a protein found on the surface of ...

Lung Cancer, Non-small cell

IOV-4001 in Melanoma or Non-Small-Cell Lung Cancer

The purpose of this study is to determine whether an investigational drug called IOV-4001 is safe and beneficial in the treatment of patients with unresectable or metastatic melanoma or advanced non-small cell lung cancer (NSCLC). ...