Find Clinical Trials | Cedars-Sinai

140 results found

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Nivolumab and Relatlimab in Advanced Mismatch Repair Deficient Cancers

The purpose of this study is to evaluate how the combination of the drugs nivolumab and relatlimab might work in people with advanced cancer that is “microsatellite instability high” (MSI-H). Microsatellite instability is a marker ...

Myeloid and Monocytic Leukemia

MYELOMATCH, Master Screening and Reassessment Protocol

In this study, researchers will plan various treatment substudies for people with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) who have not yet started treatment. Participants will be asked to undergo testing on their ...

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Dinutuximab Added to Intensive Multimodal Therapy for Children with Neuroblastoma

The purpose of this study is to compare the outcomes of a drug called dinutuximab, given early with induction therapy, to the effects of standard induction therapy with the addition of dinutuximab later in therapy, ...

Cervix, Kidney, Lung, Other Female Genital, Pancreas, Rectum, Small Intestine

KO-2806 in Adult Patients With Advanced Solid Tumors

The purpose of this study is to determine the highest tolerable dose of an investigational drug called KO-2806 in combination with an approved therapy called cabozantinib, in people with renal cell carcinoma (RCC) of predominantly ...

Lung

LY3537982 and Pembrolizumab vs Placebo and Pembrolizumab in Non-Small Cell Lung Cancer

The purpose of this study is to determine whether the addition of an investigational drug called LY3537982 to the current standard-of-care treatment (immunotherapy +/- chemotherapy) helps control cancer for a longer period of time and ...