Find Clinical Trials | Cedars-Sinai

155 results found

Colon, Lip, Oral Cavity and Pharynx, Melanoma, Pancreas

IPN01194 as Single Agent in Advanced Solid Tumors

The purpose of this study is to evaluate an experimental drug called IPN01194 in people with selected mutations in advanced solid cancers. IPN01194 is a small molecule targeting a pathway called MAPK, which is frequently ...

Anus, Bones and Joints, Brain and Nervous System, Breast, Cervix ...

Molecular Analysis for Combination Therapy Choice (ComboMATCH)

The purpose of this study is to identify patients based on gene changes or mutations in their tumor for treatment using a combination of targeted therapy. The study focuses on patients who have had a ...

Cervix

NRG, NRG-GY032, Ph2,Open-Label, Early Stage Endometrial Cancer, De-escalated adjuv or observation

Primary Objective Estimate the rate of pelvic recurrence at 3 years in patients who are treated with a de-escalated adjuvant treatment directed by tumor molecular status. Secondary Objectives Estimate the rate of isolated vaginal recurrence, para-aortic ...

Lymphoid Leukemia

Comparing Rituximab and Mosunetuzumab in Low Tumor Burden Follicular Lymphoma

The purpose of this study is to compare the usual treatment (rituximab) to an experimental drug called mosunetuzumab in people with low tumor burden follicular lymphoma. Mosunetuzumab is a type of drug known as a ...

Bones and Joints, Breast, Cervix, Colon, Esophagus, Kidney, Liver, Lung ...

MacroGenics, Inc., CP-MGC026-01, Phase 1/1b, Open Label, Multi-Center, Solid Tumors, MGC026

Primary Objective: To characterize the safety, tolerability, dose-limiting toxicities (DLTs), and maximum tolerated dose (MTD) or maximum administered dose (MAD) (if no MTD is defined) of MGC026. Secondary Objective(s): To characterize the systemic pharmacokinetics (PK) of ...