Find Clinical Trials | Cedars-Sinai

140 results found

Cervix

NRG, NRG-GY032, Ph2,Open-Label, Early Stage Endometrial Cancer, De-escalated adjuv or observation

Primary Objective Estimate the rate of pelvic recurrence at 3 years in patients who are treated with a de-escalated adjuvant treatment directed by tumor molecular status. Secondary Objectives Estimate the rate of isolated vaginal recurrence, para-aortic ...

Lymphoid Leukemia

Comparing Rituximab and Mosunetuzumab in Low Tumor Burden Follicular Lymphoma

The purpose of this study is to compare the usual treatment (rituximab) to an experimental drug called mosunetuzumab in people with low tumor burden follicular lymphoma. Mosunetuzumab is a type of drug known as a ...

Brain and Nervous System, Breast, Colon, Lung, Other Endocrine System ...

mRNA-415 in Solid Tumors

The purpose of the trial is to evaluate the safety and effects of an experimental personalized vaccine called mRNA-4157, as well as to identify the best dose for future studies, in patients who have had ...

Bones and Joints, Breast, Cervix, Colon, Esophagus, Kidney, Liver, Lung ...

MacroGenics, Inc., CP-MGC026-01, Phase 1/1b, Open Label, Multi-Center, Solid Tumors, MGC026

Primary Objective: To characterize the safety, tolerability, dose-limiting toxicities (DLTs), and maximum tolerated dose (MTD) or maximum administered dose (MAD) (if no MTD is defined) of MGC026. Secondary Objective(s): To characterize the systemic pharmacokinetics (PK) of ...

Unknown Sites

AMG 510 With or Without Panitumumab in Advanced Solid Tumors

This study focuses on individuals who have an advanced solid tumor and whose cancer has a change in the gene called KRAS G12C. The purpose of the study is to evaluate the effects of the ...