Find Clinical Trials | Cedars-Sinai

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Zanzalintinib vs Everolimus in Locally Advanced or Metastatic Neuroendocrine Tumors

The purpose of this study is to evaluate the effectiveness of an experimental drug called zanzalintinib compared to the standard-of-care treatment, everolimus, in treating people with locally advanced or metastatic neuroendocrine tumors. Zanzalintinib is a ...

Breast

RLY-2608 + Fulvestrant Versus Capivasertib + Fulvestrant as Treatment for HR+/HER2- Metastatic Breast Cancer

This study focuses on people who have metastatic (spread to other areas of the body) hormone receptor-positive, human epidermal growth factor 2-negative (HR+/HER2-) breast cancer that has a mutation in a gene called PIK3CA. The ...

Anus, Breast, Colon, Liver, Lung, Pancreas, Prostate, Rectum

Phase I Study of DB-1317 in Selected Advanced/Metastatic Solid Tumors

The purpose of this Phase 1 study is to assess the safety and tolerability of an experimental drug called DB-1317 in patients with an advanced/metastatic (cancer that has spread from its original site) solid tumor ...

Anus, Breast, Cervix, Colon, Esophagus, Lip, Oral Cavity and Pharynx ...

DB-1311 in Combination With BNT327 or DB1305 in Advanced/Metastatic Solid Tumors

The purpose of this study is to evaluate the safety and tolerability of 2 experimental drug combinations in people who have been diagnosed with an advanced/metastatic (cancer that has spread from where it started) solid ...

Prostate

Xaluritamig vs Cabazitaxel or Second Androgen Receptor-Directed Therapy in Metastatic Prostate Cancer

The purpose of this study is to determine the safety and effectiveness of an experimental drug called xaluritamig when compared to standard treatments in people with prostate cancer that has spread to other parts of ...