Find Clinical Trials | Cedars-Sinai

159 results found

Colon, Lung, Melanoma, Rectum

ModernaTX, Inc., mRNA-4359-P101, Phase 1/2, mRNA-4359 Alone and in Combo, Advanced Solid Tumors

Primary Objective: To assess the safety and tolerability of mRNA-4359 administered alone and in combination with pembrolizumab. Secondary Objectives: To assess the antitumor activity of mRNA-4359 alone and in combination with pembrolizumab. To measure and assess T cell ...

Prostate

SWOG, S1802, Ph III, Randomized, Prostate Ca, SST vs SST + surgery or radiation

Primary Objective: To compare overall survival in metastatic prostate cancer patients who are randomized to standard systemic therapy (SST) plus definitive treatment of the primary tumor versus standard systemic therapy alone. Secondary Objectives: I. To compare overall survival ...

Small Intestine, Stomach

GSK, GSK300383, Ph3, randomized, GIST, IDRX-42 (GSK6042981) versus Sunitinib

Primary Objective: To compare the efficacy of IDRX-42 (GSK6042981) to that of sunitinib in participants with metastatic and/or unresectable GIST after failure of imatinib therapy, as evidenced by PFS Key secondary: To compare the efficacy of IDRX-42 ...

Breast

CSMC, IIT2024-02-SHIAO-ASTRAEA, Ph 2, Open, Breast Ca, Radiation + Immunotherapy/SOC

Primary Objective: To establish ORR of combination therapy of stereotactic radiation, pembrolizumab, and CSF-1R inhibitor in metastatic TNBC patients who received prior immunotherapy. Secondary Objectives: To determine the safety, toxicity, and tolerability of ...