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AeviceMD for Pediatric Asthma Management

This study focuses on children who have been diagnosed with asthma. The goal of the study is to evaluate the use of a wearable medical device that can conduct continuous monitoring of vital signs and ...


Kidney

COG, AREN1921, Ph2, Open-label, DAWT + FHWT, chemotherapy

Primary Aims 1.1.1 To evaluate whether the addition of vincristine/irinotecan to cyclophosphamide/ carboplatin/etoposide alternating with vincristine/doxorubicin/cyclophosphamide improves the event-free survival (EFS) of patients with newly diagnosed Stage 4 diffuse anaplastic Wilms tumor (DAWT) as compared to historical controls. 1.1.2 To ...


Unknown Sites

Dinutuximab Added to Intensive Multimodal Therapy for Children with Neuroblastoma

The purpose of this study is to compare the outcomes of a drug called dinutuximab, given early with induction therapy, to the effects of standard induction therapy with the addition of dinutuximab later in therapy, ...


Unknown Sites

Newly Diagnosed Very Low-risk and Low-Risk Fusion Negative Rhabdomyosarcoma

This study focuses on people who have been diagnosed with rhabdomyosarcoma (RMS), a type of cancer that occurs in the soft tissues of the body and whose cancer is considered low-risk (LR-RMS). The purpose of ...


Other

Intra-Amniotic ER004 as a Prenatal Treatment for Males With X-linked Hypohidrotic Ectodermal Dysplasia

The purpose of this study is to assess the effectiveness and safety of intra-amniotic administrations (injection into amniotic fluid) of an experimental drug called ER004 in male fetuses with X-linked hypohidrotic ectodermal dysplasia (XLHED). XLHED ...