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39 results found


Brain and Nervous System

Chemotherapy Followed By WVSCI For Non-Germinomatous Central Nervous System Germ Cell Tumor

This study focuses on individuals who have been diagnosed with a type of brain cancer called non-germinomatous germ cell tumor (NGGCT) and whose tumor is “localized” (has not spread to other parts of the brain ...


Other

Outcomes of Children Newly Diagnosed with Crohn’s Disease

The purpose of this study is to determine the reasons why some children with newly diagnosed Crohn’s disease (CD) heal their bowel inflammation after one type of therapy and why others do not. CD is ...


Other

AeviceMD for Pediatric Asthma Management

This study focuses on children who have been diagnosed with asthma. The goal of the study is to evaluate the use of a wearable medical device that can conduct continuous monitoring of vital signs and ...


Kidney

COG, AREN1921, Ph2, Open-label, DAWT + FHWT, chemotherapy

Primary Aims 1.1.1 To evaluate whether the addition of vincristine/irinotecan to cyclophosphamide/ carboplatin/etoposide alternating with vincristine/doxorubicin/cyclophosphamide improves the event-free survival (EFS) of patients with newly diagnosed Stage 4 diffuse anaplastic Wilms tumor (DAWT) as compared to historical controls. 1.1.2 To ...


Non-Hodgkin's Lymphoma

Nivolumab With Chemo-Immunotherapy for the Treatment of Primary Mediastinal B-Cell Lymphoma

This study focuses on individuals who have been diagnosed with primary mediastinal B Cell lymphoma (PMBCL). PMBCL is a type of cancer that occurs in the upper chest (in an area called the mediastinum). The ...