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325 results found


Brain Injury

ICECAP

Brain injury causing coma after cardiac arrest can be fatal or may prevent patients from recovering. This study focuses on comatose, adult survivors of out-of-hospital cardiac arrest that have already been rapidly cooled per standard ...


Esophagus

DKN-01 in Combination With Tislelizumab ± Chemotherapy in Gastric or Gastroesophageal Junction Adenocarcinoma

This study focuses on people who have advanced gastric or gastroesophageal junction (GEJ) cancer. The purpose of this study is to evaluate the safety and effectiveness of an investigational drug called DKN-01 combined with another ...


ATTR-CM, Cardiac Amyloidosis

Cardiac Amyloidosis: Strategy to Improve Patient Outcomes by Silencing TTR Formation in ATTR-CM (TTRansform)

- To evaluate the effect of treatment with ION-682884 compared to placebo for 120 weeks on the composite endpoint of cardiovascular (CV) mortality and frequency of CV clinical events in patients with ATTR-CM receiving available ...


Movement Disorders

ADROIT

This data collection study focuses on individuals who are scheduled to receive an Abbott Deep Brain Stimulation (DBS) systems implant to help treat their movement disorder. DBS therapy uses small electrical pulses at a specific ...


Amyotrophic lateral sclerosis (ALS)

The HEALEY ALS Platform Trial

The purpose of the HEALEY ALS Platform Trial is to evaluate the safety and effectiveness of multiple treatments for amyotrophic lateral sclerosis (ALS). A regimen is a specific course of treatment, each with a different ...