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Terazosin and Parkinson's Disease: A Follow-Up Study

The purpose of this study is to investigate the long-term effects of treatment with the medication terazosin on imaging exams in a population of 15 subjects with defined pre-motor Parkinson`s disease (PD) risks (i.e., REM ...


Other

Induction Therapy with PRA023 in Ulcerative Colitis

This study focuses on individuals with ulcerative colitis (UC) that has been assessed as being moderate to severe. The purpose of the study is to determine whether an investigational drug called PRA023 is safe and ...


Other

Pulmonary Embolism: Safety and Outcomes of Indigo Aspiration System

This study focuses on individuals who have had a pulmonary embolism (PE) and whose doctor has determined that the clot should be removed to prevent damage to the heart and lungs. A PE is a ...


Melanoma

ALKS 4230 as Monotherapy in Advanced Melanoma

The purpose of this study is to evaluate the effectiveness, safety, and tolerability of an experimental drug called nemvaleukin (modified interleukin-2, improves immune function towards melanoma) in people with melanoma. The study focuses on individuals ...


Heart failure

Dilated Cardiomyopathy: Perform enhanced structural and functional cardiac phenotyping (DCM CMR)

Perform enhanced structural and functional cardiac phenotyping.