Find Clinical Trials | Cedars-Sinai

387 results found

ATTR-CM, Cardiac amyloidosis

ATTR Amyloidosis With Cardiomyopathy: Expanded Access Protocol to Provide Patisiran

This study is an Expanded Access Program that focuses on individuals who have transthyretin amyloidosis with cardiomyopathy (ATTR amyloidosis with cardiomyopathy). Expanded Access Programs are a means by which investigational treatments are made available to ...

Breast, Colon, Esophagus, Kidney, Lung, Melanoma, Ovary

Shionogi, 2023P2411(aCCeleR8-001), Ph1b/2,Open,Advanced Solid Tumors,S-531011 +/- Pembrolizumab

Primary: -To evaluate the safety and tolerability of S-531011 and to determine the MTD and/or RP2D of S-531011. Secondary: - To evaluate the preliminary antitumor activity of S-531011 per RECIST version 1.1a. - To characterize the PK profile ...

Other

Aortic Stenosis: Balloon-Expandable Bioprosthetic SAPIEN X4 Transcatheter Heart Valve

The purpose of this study is to determine whether an investigational device called the Sapien X4 Transcatheter Heart Valve system is beneficial for patients with symptomatic, severe, calcific aortic stenosis. Aortic stenosis is a condition ...

Breast cancer

Deescalation Of Breast Radiation for Treatment of Stage I Breast Cancer

This study focuses on women with low-risk breast cancer who have had lumpectomy (surgery to remove a breast lump). The purpose of the study is to compare the usual treatment of breast radiation and hormonal ...

Weight management

Endoscopic Weight Loss Therapy: Clinical Outcomes Over One year of Follow-Up

The purpose of this study is to better understand the metabolic and hormonal effects of endoscopic bariatric therapy. Specifically, researchers will examine changes in weight, quality of life, and hormonal levels after various endoscopic bariatric ...