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360 results found


Breast, Esophagus, Larynx, Lip, Oral Cavity and Pharynx, Lung, Melanoma ...

INCA33890 in Advanced or Metastatic Solid Tumors

The purpose of this study is to determine the safest and most effective dose of an experimental drug called INCA33890 in people with selected advanced or metastatic solid tumors. INCA33890 is an immune therapy (drug ...


Dementia, Geriatrics, Statin

Pragmatic Evaluation of Events and Benefits of Lipid-Lowering in Older Adults

The purpose of this study is to determine whether a drug called atorvastatin (a type of statin) can help older adults live well for a longer period of time by preventing dementia, disability, or heart ...


Other Hematopoietic

Zanubrutinib in Mantle Cell Lymphoma

This study focuses on individuals who have mantle cell lymphoma, which is a type of non-Hodgkin lymphoma. Zanubrutib is a drug approved by the U.S. Food and Drug Administration (FDA) for use in mantle cell ...


Hodgkin's Lymphoma, Leukemia, not otherwise specified, Leukemia, other, Lymphoid Leukemia ...

Collecting and Combining Autologous Hematopoietic Stem Cells With (CAR) T-Cell Therapy in Hematological Malignancies

The purpose of this study is to assess the impact of adding blood stem cells to CAR T-cell therapy in an effort to improve cancer treatment. CAR T-cell therapy is a type of treatment in ...


Other

Simvastatin Treatment to Improve Patient-Reported Outcomes in Chronic Pancreatitis

The purpose of this pilot study is to evaluate a drug called simvastatin for potential treatment of adults with recurrent acute pancreatitis or chronic pancreatitis. Participants will receive simvastatin or placebo (inactive substance); they will ...