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325 results found


Other Hematopoietic

Zanubrutinib in Mantle Cell Lymphoma

This study focuses on individuals who have mantle cell lymphoma, which is a type of non-Hodgkin lymphoma. Zanubrutib is a drug approved by the U.S. Food and Drug Administration (FDA) for use in mantle cell ...


Other

Simvastatin Treatment to Improve Patient-Reported Outcomes in Chronic Pancreatitis

The purpose of this pilot study is to evaluate a drug called simvastatin for potential treatment of adults with recurrent acute pancreatitis or chronic pancreatitis. Participants will receive simvastatin or placebo (inactive substance); they will ...


Other

Intraoperative Monitoring: Lateral Lumbar Interbody Fusion Procedure

The purpose of this study is to document the usefulness of an intraoperative neuromonitoring (IONM) system that is already established and approved by the U.S. Food and Drug Administration (FDA). The system is used to ...


Other

Volumetric Echocardiographic Particle Image Velocimetry in Mitral Valve Regurgitation

The purpose of this study is to evaluate a technique to measure the severity of leakage of the mitral valve in people with mitral valve regurgitation. Mitral valve regurgitation is a condition which, if untreated ...


Bones and Joints, Breast, Cervix, Colon, Kidney, Liver, Lung, Melanoma ...

PARG Inhibitor IDE161 in Advanced Solid Tumors

This study focuses on individuals who have a solid tumor cancer (not a blood cancer) that has worsened and has not responded to at least one prior cancer treatment. The purpose of the study is ...