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385 results found


Anus, Bones and Joints, Brain and Nervous System, Breast, Cervix ...

Molecular Analysis for Combination Therapy Choice (ComboMATCH)

The purpose of this study is to identify patients based on gene changes or mutations in their tumor for treatment using a combination of targeted therapy. The study focuses on patients who have had a ...


Alzheimer's disease, Dementia, Geriatrics

Repurposing Nucleoside Reverse Transcriptase Inhibitors for Treatment of Alzheimer's Disease

The purpose of this study is to determine whether a medication called emtricitabine is safe and tolerable in people with mild to moderate Alzheimer’s disease (AD). Researchers also want to learn whether emtricitabine has the ...


Cervix

NRG, NRG-GY032, Ph2,Open-Label, Early Stage Endometrial Cancer, De-escalated adjuv or observation

Primary Objective Estimate the rate of pelvic recurrence at 3 years in patients who are treated with a de-escalated adjuvant treatment directed by tumor molecular status. Secondary Objectives Estimate the rate of isolated vaginal recurrence, para-aortic ...


Lymphoid Leukemia

Comparing Rituximab and Mosunetuzumab in Low Tumor Burden Follicular Lymphoma

The purpose of this study is to compare the usual treatment (rituximab) to an experimental drug called mosunetuzumab in people with low tumor burden follicular lymphoma. Mosunetuzumab is a type of drug known as a ...


Other

Clofazimine Inhalation Suspension in Pulmonary Nontuberculous Mycobacterial Infection

This study focuses on people who have been diagnosed with non-tuberculous mycobacteria (NTM) lung disease. The purpose of the study is to determine whether an experimental drug called clofazimine inhalation suspension can treat NTM lung ...