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354 results found


Melanoma

GIM-531 as a Single Agent and in Combination With Anti-PD-1 in Advanced Solid Tumors

This study focuses on individuals who have been diagnosed with advanced stage cancer. The purpose of the study is to determine whether an experimental drug called GIM-531 is safe and can help the immune system ...


Other

Advancing Transplantation Outcomes in Children

This study focuses on pediatric patients who are receiving a kidney transplant at Cedars-Sinai. The purpose of the study is to determine whether an experimental combination of immunosuppressive drugs, belatacept and sirolimus, preserves kidney ...


Melanoma

OBX-115 in Unresectable or Metastatic Melanoma

The goal of this study is to determine the recommended dose of an experimental cell therapy called OBX-115 with another medication called acetazolamide (approved by the U.S. Food and Drug Administration as a mild diuretic) ...


Other

Pulmonary Embolism - Thrombus Removal With Catheter-Directed Therapy

The goal of this study is to identify the best way to treat pulmonary embolism (blood clots in the lungs), specifically when there is a large amount of clot, but the patient’s blood pressure is ...


Melanoma

Vusolimogene Oderparepvec in Combination With Nivolumab in Advanced Melanoma

The purpose of this study is to evaluate an experimental drug called vusolimogene oderparepvec (VO) in combination with another drug, nivolumab, in people who have advanced melanoma. Researchers will compare the effects of nivolumab with ...