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325 results found


Unknown Sites

Dinutuximab Added to Intensive Multimodal Therapy for Children with Neuroblastoma

The purpose of this study is to compare the outcomes of a drug called dinutuximab, given early with induction therapy, to the effects of standard induction therapy with the addition of dinutuximab later in therapy, ...


Cervix, Kidney, Lung, Other Female Genital, Pancreas, Rectum, Small Intestine

KO-2806 in Adult Patients With Advanced Solid Tumors

The purpose of this study is to determine the highest tolerable dose of an investigational drug called KO-2806 in combination with an approved therapy called cabozantinib, in people with renal cell carcinoma (RCC) of predominantly ...


Other

Continued Access Study of the ShortCut Device

The purpose of this study to determine whether an experimental device called the ShortCut is safe and effective in people with a risk for coronary obstruction following a repeated bioprosthetic valve implantation. Coronary obstruction is ...


Unknown Sites

Newly Diagnosed Very Low-risk and Low-Risk Fusion Negative Rhabdomyosarcoma

This study focuses on people who have been diagnosed with rhabdomyosarcoma (RMS), a type of cancer that occurs in the soft tissues of the body and whose cancer is considered low-risk (LR-RMS). The purpose of ...


Other

Hearts Transplanted After Non-Ischemic Heart Preservation from Extended Donors

The purpose of this study is to evaluate whether non-ischemic heart preservation (NIHP) of extended criteria donor hearts using the XVIVO Heart Preservation System (XHPS) is a safe and effective way to preserve and transport ...