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387 results found


Breast

Adjuvant Sacituzumab Govitecan and Pembrolizumab in Triple-Negative Breast Cancer

The purpose of this study is to evaluate an experimental drug called sacituzumab govitecan in combination with pembrolizumab, or pembrolizumab with or without capecitabine, in people with high-risk, early triple-negative breast cancer without mutations (changes) ...


Multiple Myeloma

ABBV-383 Compared With Standard Available Therapies in Relapsed or Refractory Multiple Myeloma

The purpose of this study is to evaluate the safety and effectiveness of an experimental drug called ABBV-383 in people with relapsed or refractory multiple myeloma (multiple myeloma that has come back or did not ...


Lung

Merck,MK-2870-019, Ph3, Open label randomized, Pembrolizumab +/- MK-2870 , NSCLC

Primary Objective: Objective: To compare MK-2870 plus pembrolizumab versus pembrolizumab monotherapy with respect to DFS as assessed by BICR. DFS: the time from randomization to any recurrence (local, locoregional, regional or distant), occurrence of new primary NSCLC, or ...


Other

Mavacamten in Symptomatic Obstructive Hypertrophic Cardiomyopathy

This study focuses on people who have been diagnosed with obstructive hypertrophic cardiomyopathy (oHCM), a condition in which the heart muscle thickens and blocks blood flow from the heart. The purpose of the study is ...


Other

Long-Term Safety and Efficacy of NNC6019-0001 in Transthretin Amyloid Cardiomyopathy

The purpose of this study is to evaluate the long-term safety and effectiveness of a medicine called NNC6019-0001 in people who have heart failure due to transthyretin (TTR) amyloidosis (build-up of abnormal protein in heart ...