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396 results found


Leukemia, other

Venetoclax Plus Chemotherapy For Newly Diagnosed Acute Myeloid Leukemia

This study focuses on people who have a new diagnosis of acute myeloid leukemia (AML) who agreed to participate in the MyeloMATCH study and were matched to this treatment trial. The purpose of the study ...


Other

JenaValve Trilogy Transcatheter Heart Valve System Versus Surgical Valve Replacement in Aortic Regurgitation

The purpose of this study is to determine whether an experimental device called the Trilogy Transcatheter Heart Valve (THV) System is as effective as surgical valve replacement (SAVR) in treating moderate-to-severe or severe aortic regurgitation ...


Unknown Sites

Neoadjuvant Immunotherapy With Response-Adapted Treatment in Resectable Stage III/IV Cutaneous Squamous Cell Carcinoma

This study focuses on people who have advanced squamous cell skin cancer that can be removed with surgery. The purpose of the study is to determine whether giving an immunotherapy drug called cemiplimab before and ...


Lip, Oral Cavity and Pharynx

Using Circulating Tumor DNA to Risk Adapt Post-Operative Therapy for HPV-Associated Oropharyngeal Cancer

The purpose of this study is to determine whether using less intense radiation therapy and chemotherapy (chemoradiation) after trans-oral robotic surgery (TORS) will be as effective in treating HPV-associated oropharyngeal cancer as standard treatment while ...


Other

J-Valve to Treat Aortic Regurgitation via Transcatheter Therapy

The purpose of this study is to learn about the safety and performance of an experimental device called the J-Valve TF System. The device is designed to treat severe aortic regurgitation, (AR). AR occurs when ...