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382 results found


Brain and Nervous System

Glioblastoma Accelerated Biomarkers Learning Environment Trial

The purpose of this study is to identify new biological markers (specific biological features) associated with scans of a brain tumor that will help doctors predict how tumors might develop and affect the health of ...


Other

Sotagliflozin in Symptomatic Obstructive And Non-Obstructive Hypertrophic Cardiomyopathy

The purpose of this study is to determine whether an experimental drug called sotagliflozin is effective in treating symptoms related to hypertrophic cardiomyopathy (HCM). HCM is a common heart condition that causes the heart muscle ...


Other

Tulisokibart in Moderately to Severely Active Crohn's Disease

The purpose of this study is to evaluate the safety and effectiveness of an experimental drug called tulisokibart (MK-7240) in people with moderately to severely active Crohn’s disease that has not responded well to treatment. ...


Other Digestive Organ

AZD0901 Monotherapy Compared With Investigator’s Choice of Therapy in Advanced/Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma

The purpose of this study is to evaluate the effectiveness and safety of an experimental drug called AZD0901 compared to a standard therapy selected by the participant’s study doctor (per their disease status) and to ...


Other

Laminar Left Atrial Appendage Elimination Pivotal IDE Study

The purpose of this study is to compare the safety and effectiveness of an experimental device called the Laminar Left Atrial Appendage Closure System with a commercially available left atrial appendage closure device that is ...