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319 results found


Breast, Melanoma, Multiple Myeloma, Other Skin

STX-478 as Monotherapy and in Combination With Other Antineoplastic Agents in Advanced Solid Tumors

The purpose of this study is to evaluate an experimental drug called STX 478 that is designed to specifically target mutated cancer cells (cancer cells that have a change in genetic structure) with mutations in ...


Other

SELUTION SLR 014 Drug Eluting Balloon in the Treatment of In-Stent Restenosis

The purpose of this study is to demonstrate whether an investigational device called the SELUTION SLR drug eluting balloon is well tolerated and whether it works as effectively as other currently available treatments for patients ...


Breast, Esophagus, Larynx, Lip, Oral Cavity and Pharynx, Lung, Melanoma ...

INCA33890 in Advanced or Metastatic Solid Tumors

The purpose of this study is to determine the safest and most effective dose of an experimental drug called INCA33890 in people with selected advanced or metastatic solid tumors. INCA33890 is an immune therapy (drug ...


Other

Pragmatic Evaluation of Events and Benefits of Lipid-Lowering in Older Adults

The purpose of this study is to determine whether a drug called atorvastatin (a type of statin) can help older adults live well for a longer period of time by preventing dementia, disability, or heart ...


Ovary

TransCon IL-2 β/​γ in Locally Advanced or Metastatic Solid Tumor Malignancies

The purpose of this study is to evaluate the safety and effectiveness of an experimental drug called TransCon IL-2 beta/gamma when given in combination with chemotherapy or in combination with another experimental drug, TransCon TLR7/8 ...