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325 results found


Lymphoid Leukemia

Cytarabine Plus Daunorubicin Compared to Experimental Groups in High-Risk Acute Myeloid Leukemia

This study focuses on individuals who have been recently diagnosed with high-risk, acute myeloid leukemia (AML) and have not yet started treatment. Researchers want to know whether they can shrink the amount of AML or ...


Other

Combined Cardiac Contractility Modulation and Implantable Cardioverter Defibrillator Device for Heart Failure

The purpose of this study is to determine whether an investigational device called the OPTIMIZER Integra CCM-D System can effectively defibrillate (send a controlled shock to restore normal rhythm) and treat episodes of ventricular tachycardia ...


Other

Tafamidis in Patients With Transthyretin-Mediated Amyloidosis Post Orthotopic Heart Transplantation

The purpose of this study is to determine whether tafamidis, an oral medication used to delay disease progression in adults with certain forms of transthyretin amyloidosis (ATTR), is effective in treating patients with heart transplants ...


Other

MagicTouch Sirolimus-Coated Balloon in Coronary Artery Lesions of In-Stent Restenosis

The purpose of this study is to evaluate the safety and effectiveness of an experimental drug-coated balloon system called the MagicTouch sirolimus-coated balloon for the treatment of coronary in-stent restenosis (recurrence of narrowing of a ...


Melanoma

GIM-531 as a Single Agent and in Combination With Anti-PD-1 in Advanced Solid Tumors

This study focuses on individuals who have been diagnosed with advanced stage cancer. The purpose of the study is to determine whether an experimental drug called GIM-531 is safe and can help the immune system ...