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391 results found


Ovary

Olaparib With or Without Bevacizumab in BRCA 1/2 Mutated or Homologous Recombination Deficient Ovarian Cancer

This study focuses on people with ovarian cancer who have tested positive for BRCA1/2 mutation (change or defect in the BRCA gene) or homologous recombination deficiency (when the body cannot repair breaks in DNA). The ...


Other

ER004 Post-Intra-Amniotic Treatment in Males With XLHED

The purpose of this study is to evaluate the safety and effectiveness of an experimental drug called ER004 in X-linked hypohidrotic ectodermal dysplasia (XLHED) when given before birth (injected into the amniotic fluid that surrounds ...


Other

A Long-Term Study of Elafibranor in Primary Biliary Cholangitis

The purpose of this study is to learn about the long-term benefits and side effects of repeated treatment for patients with primary biliary cholangitis (PBC) and cirrhosis. PBC occurs because of inflammation and injury of ...


Other

Siegel Transcatheter Aortic Valve Replacement System EFS Study

The purpose of this study is to determine whether an experimental device called the Siegel Transcatheter Aortic Valve Replacement (TAVR) System is safe and effective in treating adults who have aortic stenosis, a condition in ...


Focal segmental glomerulosclerosis

DMX-200 in Patients With Focal Segmental Glomerulosclerosis

This study will evaluate an experimental medication called DMX 200 (repagermanium) for people with focal segmental glomerulosclerosis (FSGS). FSGS is a progressive kidney disease in which the filters (glomeruli) of the kidneys become inflamed and ...