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325 results found


Lymphoid Leukemia

Comparing Rituximab and Mosunetuzumab in Low Tumor Burden Follicular Lymphoma

The purpose of this study is to compare the usual treatment (rituximab) to an experimental drug called mosunetuzumab in people with low tumor burden follicular lymphoma. Mosunetuzumab is a type of drug known as a ...


Brain and Nervous System, Breast, Colon, Lung, Other Endocrine System ...

mRNA-415 in Solid Tumors

The purpose of the trial is to evaluate the safety and effects of an experimental personalized vaccine called mRNA-4157, as well as to identify the best dose for future studies, in patients who have had ...


Other

Clofazimine Inhalation Suspension in Pulmonary Nontuberculous Mycobacterial Infection

This study focuses on people who have been diagnosed with non-tuberculous mycobacteria (NTM) lung disease. The purpose of the study is to determine whether an experimental drug called clofazimine inhalation suspension can treat NTM lung ...


Other Digestive Organ

Folfox in Combination with Binimetinib in Advanced Biliary Tract Cancers

This study focuses on individuals who have advanced biliary tract cancer and who may have had progression of cancer after previous treatments. The purpose of the study is to compare the usual treatment alone (chemotherapy ...


Bones and Joints, Breast, Cervix, Colon, Esophagus, Kidney, Liver, Lung ...

MacroGenics, Inc., CP-MGC026-01, Phase 1/1b, Open Label, Multi-Center, Solid Tumors, MGC026

Primary Objective: To characterize the safety, tolerability, dose-limiting toxicities (DLTs), and maximum tolerated dose (MTD) or maximum administered dose (MAD) (if no MTD is defined) of MGC026. Secondary Objective(s): To characterize the systemic pharmacokinetics (PK) of ...