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Early Internal Fixation Vs. NonOperative Care With Early Rehabilitation for Fractures of the Pelvis

The purpose of this study is to evaluate whether early surgical treatment is more effective than nonoperative care and early rehabilitation at lowering the risk of complications in patients with pelvis fractures. Both options are ...


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Vutrisiran in Patients With Transthyretin Amyloidosis with Cardiomyopathy

The purpose of this study is to evaluate the safety of a drug called vutrisiran (amvuttra) and determine the effects it has on people with transthyretin amyloidosis (ATTR) with cardiomyopathy (either hereditary or wild type). ...


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SELUTION SLR Drug Eluting Balloon in De Novo Coronary Lesions in Small Vessels

The purpose of this study is to determine whether an experimental device called the SELUTION SLR drug eluting balloon is safe and whether it works as effectively as other currently available treatments for patients with ...


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Improving Deceased-Donor Kidney Transplant Outcomes Via a Single Intragraft Injection of C1 Esterase Inhibitor

This study focuses on people who are waiting for a deceased donor kidney transplant and, as determined at the time of transplant, are receiving a donated kidney at risk of damage from having decreased oxygen ...


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Felzartamab in Kidney Transplant Recipients with Late Antibody-Mediated Rejection

This study aims to learn more about the safety and effectiveness of an experimental drug called felzartamab in people who have received a kidney transplant and may have late antibody-mediated rejection (AMR). AMR is a ...