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325 results found


Unknown Sites

AMG 510 With or Without Panitumumab in Advanced Solid Tumors

This study focuses on individuals who have an advanced solid tumor and whose cancer has a change in the gene called KRAS G12C. The purpose of the study is to evaluate the effects of the ...


Other Female Genital, Unknown Sites

Neratinib Alone or in Combination with Palbociclib in HER2+ Cancers and Other Solid Tumors

This study focuses on individuals who have recurrent or persistent cancer and whose cancer expresses a protein called HER2 (human growth factor receptor 2). The purpose of the study is to determine whether a combination ...


Unknown Sites

Paclitaxel and Ipatasertib In PTEN/AKT-Altered Advanced Non-Breast Solid Tumors

The purpose of this study is to evaluate the effects of combining a drug called ipatasertib with the chemotherapy drug paclitaxel in people who have advanced cancer and whose cancer has a change in genes ...


Other

Genentech_Kirros Study_ML44719

The purpose of this study is to characterize, in patients with unresectable hepatocellular carcinoma (HCC) and Child-Pugh B7 or B8 liver cirrhosis, the safety and efficacy of atezolizumab plus bevacizumab or atezolizumab alone (in patients ...


Brain and Nervous System

Anti-Lag-3 and Anti-PD-1 Blockade Blockade Vs. SOC in Recurrent Glioblastoma

The purpose of this study is to evaluate the experimental combination of immunotherapy drugs, relatlimab and nivolumab, in people with brain cancer. The study aims to determine whether these drugs can increase the chance that ...