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323 results found

Atrial fibrillation

Paroxysmal Atrial Fibrillation: Synaptic Compliant Cryoablation Balloon and System

The purpose of this study is to determine whether an investigational medical device called the Synaptic Cryoablation System is safe and effective for treating paroxysmal atrial fibrillation. Atrial fibrillation is an abnormal heart rhythm in ...

Cervix, Esophagus, Kidney, Liver, Lung, Melanoma, Urinary Bladder

MT-8421 as Monotherapy and in Combination With Nivolumab

The purpose of this study is to evaluate the safety and efficacy of an investigational drug called MT-8421 alone and when given with another drug, nivolumab, in patients with advanced cancer. Researchers also want to ...

Colon, Liver, Other Female Genital

E7386 in Combination With Other Anticancer Drug(s) in Solid Tumors

The purpose of this study is to determine whether an experimental drug called E7386 in combination with another drug, lenvatinib, is safe and effective in people who have an advanced solid tumor, including colorectal, hepatocellular, ...

Anus, Bones and Joints, Brain and Nervous System, Breast, Cervix ...

Allogenic Blood-Derived Natural Killer Cells in Cancer Refractory to Conventional Therapy

The purpose of this study is to evaluate a blood-derived experimental therapy in patients who have refractory cancer that has failed conventional, standard-of-care therapy. Researchers will use natural killer (NK) cells to create the study ...


Shorter Anthracycline-Free Chemo Immunotherapy in Early Triple-Negative Breast Cancer

The purpose of this study is to compare the standard-of-care chemo-immunotherapy (carboplatin/paclitaxel followed by adriamycin/cyclophosphamide plus pembrolizumab, given in 6 months) treatment for early-stage, triple-negative breast cancer to a shorter non-anthracycline chemo-immunotherapy treatment (carboplatin docetaxel ...