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430 results found


Anus, Breast, Lung, Other Female Genital, Ovary, Unknown Sites

Sumitomo Pharma America, Inc, SMP-3124-101, PhI/II, Open-label, SMP-3124LP, Solid tumors

Primary Objective: Dose Escalation: Determine the Recommended Phase 2 Dose (RP2D). Assess the safety and tolerability. Dose Expansion: Evaluate preliminary antitumor activity. Secondary Objectives: Dose Escalation: Establish the plasma PK profile of SMP-3124 and SMP-3124LP. Evaluate ...


Breast, Cervix, Lung, Other Digestive Organ, Other Female Genital, Ovary ...

BL-M07D1 in Subjects With HER2 Expressing Advanced Malignant Solid Tumors

The purpose of this study is to evaluate the safety, tolerability, and effectiveness of an experimental drug called BL-M07D1 as a possible treatment for people who have a type of advanced, inoperable cancer that expresses ...


Other

WATCHMAN FLX Pro Left Atrial Appendage Closure Device With Alternative Post-Implant Monotherapy

This study focuses on people who have a heart condition called atrial fibrillation (AFib). AFib can cause blood to pool in a part of the heart called the left atrial appendage, where blood clots can ...


Other

ION582 in Children and Adults with Angelman Syndrome

The purpose of this study is to determine the safety and effectiveness of an experimental drug called ION582 in children and adults with Angelman syndrome. Angelman syndrome is a rare genetic condition resulting in severe developmental ...


Other

Manual T-Piece Vs. Ventilator Positive Pressure Ventilation During Resuscitation of Extremely Premature Neonates

The purpose of this study is to determine whether one method of positive pressure ventilation (PPV) delivery is more effective than the other in premature babies. Extremely premature infants often need breathing support immediately after ...