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415 results found


Colon, Other Digestive Organ, Pancreas, Rectum

A Platform Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors

This study focuses on people who have either advanced colorectal cancer or advanced pancreatic cancer that is driven by a gene known as RAS. The purpose of the study is to evaluate the safety of ...


Solid Tumors

Bristol-Myers Squibb, CA2360001, Ph 1/2, Open-Label, Multi-center, NSCLC, BMS-986482, Solid Tumor

Primary : To assess the safety and tolerability of oral BMS-986482, as monotherapy or in combination with nivolumab SC, nivolumab + relatlimab FDC SC, or bevacizumab, to establish the MTD,MAD, and/or RP2D(s) in participants with advanced solid ...


Liver

SIRT with Tremelimumab and Durvalumab for Resectable Hepatocellular Carcinoma

This study focuses on people who have liver cancer (hepatocellular carcinoma-HCC) for which they will be undergoing surgical treatment. The purpose of the study is to evaluate the safety and tolerability of neoadjuvant treatment (treatment ...


Other

Registry of Deep Brain Stimulation with the VERCISE System

The purpose of this study is to collect real-world information on effects of a device called the Vercise Deep Brain Stimulation (DBS) system for treatment of patients with Parkinson's disease that is not well-controlled with ...


Other

CSL300 (Clazakizumab) in Patients With End-Stage Kidney Disease Undergoing Dialysis

The purpose of this study is to determine whether a drug called CSL300 (clazakizumab) is effective and safe in patients on maintenance dialysis for reducing the risk of death from a heart attack or heart-related ...