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NTX-001 Compared to Standard of Care in Upper Extremity Transected Nerves Requiring Surgical Repair

This study focuses on people who have experienced a particular type of nerve injury involving a peripheral nerve in their fingers, hand or arm in which the nerve(s) has/have been completely severed, and the injury ...


Breast

Bria-IMT Regimen With Check Point Inhibitor vs Physician’s Choice in Metastatic Breast Cancer

The purpose of this study is to assess the safety and effectiveness of an experimental therapy for advanced breast cancer called Bria-IMT (SV-BR-1-GM) cancer vaccine in combination with immune checkpoint inhibitor retifanlimab. Retifanlimab can help ...


Lung

BNT324 with BNT327 in Participants With Advanced Lung Cancer

The purpose of this study is to assess whether the investigational drugs BNT324 and BNT327 can help control advanced or metastatic lung cancer. The study aims to determine the most suitable combination dose of BNT324 ...


Unknown Sites

VEGFR2/MET Inhibitor Cabozantinib in Combination With Cytotoxic Chemotherapy for Newly Diagnosed Osteosarcoma

This study focuses on individuals who have a type of bone cancer called osteosarcoma (OST). The purpose of the study is to evaluate how well an experimental drug called cabozantinib works in combination with methotrexate, ...


Other

Microvascular Aging Effects

The purpose of this study is to better understand how aging affects the heart, brain, and muscles, as well as how these changes may lead to conditions such as heart failure, memory loss and dementia, ...