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331 results found


Movement Disorders

Safety and Efficacy of AMX0035 in Progressive Supranuclear Palsy

This study focuses on people who have been diagnosed with progressive supranuclear palsy (PSP) or have a probable diagnosis of PSP. PSP is a nervous system disease that affects nerve cells in the brain and ...


Other

AltaValve Pivotal Trial Protocol

The purpose of this study is to evaluate the safety and effectiveness of an experimental device called the AltaValve System in people with moderate-to-severe and severe mitral regurgitation. The study aims to determine whether the ...


Other

Levosimendan in PH-HFpEF

This study focuses on people who have pulmonary hypertension with heart failure with preserved ejection fraction (PH-HFpEF), also known as diastolic heart failure or diastolic dysfunction. This is a type of heart failure in which ...


Corpus Uteri, Ovary

Selumetinib and Olaparib or Selumetinib Alone in Ovarian and Endometrial Cancers

This study focuses on people who have recurrent or persistent ovarian or endometrial cancer and whose cancer has a change in the gene family called RAS genes. The purpose of the study is to compare ...


Breast

Adjuvant Sacituzumab Govitecan and Pembrolizumab in Triple-Negative Breast Cancer

The purpose of this study is to evaluate an experimental drug called sacituzumab govitecan in combination with pembrolizumab, or pembrolizumab with or without capecitabine, in people with high-risk, early triple-negative breast cancer without mutations (changes) ...