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Elafribanor in Patients With Primary Biliary Cholangitis Receiving Treatment in a Real- World Setting

The purpose of this study is to gain insight into the safety and effectiveness of a drug called elafibranor for the treatment of primary biliary cholangitis (PBC) in a real-world (routine care) setting. PBC is ...


Other

Registry: GORE TAG Conformable Thoracic Stent Graft With Active Control System

The purpose of this registry study is to collect data over time about the use and continuing safety of a medical device called the GORE TAG Conformable Thoracic Stent Graft with Active Control System and ...


Leukemia, other

Venetoclax Plus Chemotherapy For Newly Diagnosed Acute Myeloid Leukemia

This study focuses on people who have a new diagnosis of acute myeloid leukemia (AML) who agreed to participate in the MyeloMATCH study and were matched to this treatment trial. The purpose of the study ...


Other

JenaValve Trilogy Transcatheter Heart Valve System Versus Surgical Valve Replacement in Aortic Regurgitation

The purpose of this study is to determine whether an experimental device called the Trilogy Transcatheter Heart Valve (THV) System is as effective as surgical valve replacement (SAVR) in treating moderate-to-severe or severe aortic regurgitation ...


Colon, Lung, Melanoma, Other Female Genital, Thyroid, Unknown Sites

KIN-2787 in Participants With BRAF and/or NRAS Mutation-Positive Solid Tumors

This early-phase clinical trial is designed for adults with advanced solid tumors that have spread (metastasized) and carry specific genetic mutations in the BRAF and/or NRAS genes—both of which are known to drive cancer progression. ...