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421 results found

Solid Tumors

Bristol-Myers Squibb, CA2360001, Ph 1/2, Open-Label, Multi-center, NSCLC, BMS-986482, Solid Tumor

Primary : To assess the safety and tolerability of oral BMS-986482, as monotherapy or in combination with nivolumab SC, nivolumab + relatlimab FDC SC, or bevacizumab, to establish the MTD,MAD, and/or RP2D(s) in participants with advanced solid ...

Liver

SIRT with Tremelimumab and Durvalumab for Resectable Hepatocellular Carcinoma

This study focuses on people who have liver cancer (hepatocellular carcinoma-HCC) for which they will be undergoing surgical treatment. The purpose of the study is to evaluate the safety and tolerability of neoadjuvant treatment (treatment ...

Other

Registry of Deep Brain Stimulation with the VERCISE System

The purpose of this study is to collect real-world information on effects of a device called the Vercise Deep Brain Stimulation (DBS) system for treatment of patients with Parkinson's disease that is not well-controlled with ...

Other

CSL300 (Clazakizumab) in Patients With End-Stage Kidney Disease Undergoing Dialysis

The purpose of this study is to determine whether a drug called CSL300 (clazakizumab) is effective and safe in patients on maintenance dialysis for reducing the risk of death from a heart attack or heart-related ...

Lung

Incorporating Pathologic Complete Response in Non-Small Cell Lung Cancer to Optimize Immunotherapy

The purpose of this study is to compare the usual approach of observation (closely watching a patient’s condition after surgery) to taking an immunotherapy drug, durvalumab (MEDI4736), in people with early-stage, non-small cell lung cancer ...