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CSL300 (Clazakizumab) in Patients With End-Stage Kidney Disease Undergoing Dialysis

The purpose of this study is to determine whether a drug called CSL300 (clazakizumab) is effective and safe in patients on maintenance dialysis for reducing the risk of death from a heart attack or heart-related ...


Lung

Incorporating Pathologic Complete Response in Non-Small Cell Lung Cancer to Optimize Immunotherapy

The purpose of this study is to compare the usual approach of observation (closely watching a patient’s condition after surgery) to taking an immunotherapy drug, durvalumab (MEDI4736), in people with early-stage, non-small cell lung cancer ...


Other

Itepekimab in Inadequately Controlled Chronic Rhinosinusitis With Nasal Polyps

This study focuses on people who have chronic rhinosinusitis (inflammation or swelling of the tissues lining the sinuses and the nose). The study will evaluate the effectiveness, safety, and tolerability of an experimental drug called ...


Other

Follow-up Study of the Serranator PTA Serration Balloon Catheter

This study focuses on people who have peripheral artery disease or a dysfunctional arteriovenous fistula and will be treated as part of routine standard care with a device called the Serranator PTA Serration Balloon Catheter ...


Other

Zorevunersen (STK-001) in Patients With Dravet Syndrome

The purpose of this study is to determine whether an experimental drug called zorevunersen (STK-001) works to reduce the number of seizures for children and adolescents with Dravet syndrome. Dravet syndrome is a severe form ...