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319 results found


Other Hematopoietic

Malignancies Treated With CRISPR CAR Cellular Therapies

The purpose of this study is to evaluate long-term safety and effectiveness of an experimental treatment (gene-edited therapy) called CRISPR-Cas/9—engineered CAR cell therapy in patients who received these cells for treatment of cancer as part ...


Breast

AstraZeneca AB, D0817C00098, Ph3b, open label rollover, Breast Cancer, continuation of Olaparib

Primary Objective: To provide continuous study treatment to patients who continue to benefit at the end of a clinical trial, while monitoring safety and tolerability.


Unknown Sites

Nivolumab and Relatlimab in Advanced Mismatch Repair Deficient Cancers

The purpose of this study is to evaluate how the combination of the drugs nivolumab and relatlimab might work in people with advanced cancer that is “microsatellite instability high” (MSI-H). Microsatellite instability is a marker ...


Unknown Sites

COG, ANBL2131, Ph 3, Randomized, Neuroblastoma, Dinutuximab + induction chemo

PRIMARY OBJECTIVE: I. To determine if the event-free survival (EFS) of patients with newly diagnosed high-risk neuroblastoma assigned to early chemoimmunotherapy during Induction differs from that of patients who are not assigned to treatment that includes ...