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331 results found


Multiple Myeloma

ABBV-383 Compared With Standard Available Therapies in Relapsed or Refractory Multiple Myeloma

The purpose of this study is to evaluate the safety and effectiveness of an experimental drug called ABBV-383 in people with relapsed or refractory multiple myeloma (multiple myeloma that has come back or did not ...


Other

Dupilumab in Adult and Adolescent Patients With Eosinophilic Gastritis With or Without Eosinophilic Duodenitis

The purpose of this study is to evaluate an experimental drug called dupilumab in people with active eosinophilic gastritis (EoG) with or without eosinophilic duodenitis (EoD). EoG and EoD are persistent allergic/immune diseases in which ...


Lung

Merck,MK-2870-019, Ph3, Open label randomized, Pembrolizumab +/- MK-2870 , NSCLC

Primary Objective: Objective: To compare MK-2870 plus pembrolizumab versus pembrolizumab monotherapy with respect to DFS as assessed by BICR. DFS: the time from randomization to any recurrence (local, locoregional, regional or distant), occurrence of new primary NSCLC, or ...


Other

Mavacamten in Symptomatic Obstructive Hypertrophic Cardiomyopathy

This study focuses on people who have been diagnosed with obstructive hypertrophic cardiomyopathy (oHCM), a condition in which the heart muscle thickens and blocks blood flow from the heart. The purpose of the study is ...


Pancreas

RMC-6236 Versus Standard-of-Care Therapy in Previously Treated Metastatic Pancreatic Ductal Adenocarcinoma

The purpose of this study is to evaluate an experimental drug called RMC-6236 in pancreatic cancer patients whose cancer has spread outside the pancreas (metastatic) and whose cancer has returned after treatment or did not ...