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352 results found


Urinary Bladder

Bladder Preservation for Patients With Muscle Invasive Bladder Cancer With Variant Histology

The goal of this study is to evaluate a treatment called trimodal therapy after a course of neoadjuvant therapy (treatment given as a first step to shrink a tumor before main treatment) as a way ...


Brain and Nervous System, Melanoma, Other Hematopoietic, Soft Tissue

Cobolimab in Combination with Dostarlimab in Pediatric and Young Adult Participants With Newly Diagnosed and Relapsed/Refractory Tumors

The purpose of this study is to evaluate an experimental drug called cobolimab, given with dostarlimab (an anti-cancer medication used in adults) in children, teens, and young adults whose cancer has spread to other parts ...


Other

MK-7240 in Moderately to Severely Active Ulcerative Colitis

The purpose of this research is to evaluate the safety and effectiveness of an experimental drug called MK-7240 (tulisokibart) compared with placebo (inactive substance) in people with moderately to severely active ulcerative colitis. There are ...


Other

Pirfenidone Solution for Inhalation (AP01) in Progressive Pulmonary Fibrosis

The purpose of this study is to evaluate the safety and effectiveness of multiple doses of an experimental drug called AP01 compared with placebo (inactive substance) in people who have progressive pulmonary fibrosis (PPF). The ...


Brain and Nervous System

Glioblastoma Accelerated Biomarkers Learning Environment Trial

The purpose of this study is to identify new biological markers (specific biological features) associated with scans of a brain tumor that will help doctors predict how tumors might develop and affect the health of ...