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396 results found


Obesity

Evaluating Environmental Control (AVOID) and Inhibitory Control (RESIST) Strategies to Improve Weight Management Outcomes

This study tests strategies to help adults with overweight or obesity (BMI between 25-45 kg/m2) “stick” to weight management recommendations. Specifically, the study evaluates the benefit of 2 self-regulatory approaches to improve intentional weight loss ...


Melanoma

Cemiplimab plus Ziv-Aflibercept in Metastatic Uveal Melanoma

The purpose of this phase II study for advanced melanoma is to evaluate the safety (side effects profile) and effectiveness (tumor shrinkage) of cemiplimab and ziv-aflibercept, when given together. Cemiplimab is an anti-cancer drug called ...


Melanoma

Fianlimab, Cemiplimab, and Ipilimumab in Anti-PD-1 Refractory Melanoma

The purpose of this study is to determine whether the drug combination of fianlimab, cemiplimab, and ipilimumab is a safe and effective treatment for refractory melanoma. The study focuses on people whose melanoma has spread ...


Breast

Ivonescimab in Combination With Carboplatin + Docetaxel in Early Stage Triple Negative Breast Cancer

The purpose of this study is to evaluate the safety and effectiveness of an experimental drug called ivonescimab when combined with standard chemotherapy (carboplatin and docetaxel) before surgery for the treatment of early stage, triple-negative ...


Other

Early Internal Fixation Vs. NonOperative Care With Early Rehabilitation for Fractures of the Pelvis

The purpose of this study is to evaluate whether early surgical treatment is more effective than nonoperative care and early rehabilitation at lowering the risk of complications in patients with pelvis fractures. Both options are ...