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MGL-3196 in Non-Alcoholic Steatohepatitis and Fibrosis

The purpose of this study is to evaluate the effects of an investigational drug called MGL-3196 on individuals with nonalcoholic steatohepatitis (NASH). Researchers aim to determine the safety, effectiveness and optimal dosage of MGL-3196, as ...


Pancreas

Contrast-Enhanced Endoscopic Ultrasound for Evaluation of Pancreas Lesions

The purpose of this study is to evaluate whether contrast-enhanced endoscopic ultrasound (CE-EUS) improves the characterization of pancreas tumors and precancerous lesions, including cysts, in comparison to conventional endoscopic ultrasound (EUS). Participants will be patients ...


Prostate

Mechanisms of Glutamine Metabolism in Prostate Cancer Progression

This study focuses on patients with a specific stage of prostate cancer known as metastatic, castration-sensitive or metastatic, castration-resistant prostate cancer who are still receiving androgen targeting therapy (a type of prostate cancer therapy). The ...


Lung

Biomarker-Driven Therapies and Immunotherapies in Non-Small Cell Lung Cancer

This study focuses on patients with non-small cell lung cancer. The purpose is to study tumor tissue to determine whether a targeted or immunotherapy treatment will have an effect on specific genes and proteins in ...


Other

UVA Light Device to Treat COVID-19

To demonstrate basic safety and proof of principle for Endotracheal UV Light Device. Primary Endpoint: Reduction of viral load in upper airway in patients admitted to hospital positive for COVID-19. Secondary Endpoints: Overall reduction or change for the following ...