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370 results found


Breast, Cervix, Esophagus, Kidney, Liver, Lung, Melanoma, Other Female Genital ...

Phase 1/2 Study of CRB-601 in Patients With Advanced Solid Tumors

The purpose of this study is to determine whether an experimental drug called CRB-601 can help people with advanced solid tumors (cancer). The study aims to evaluate how well the drug is tolerated and identify ...


Ovary

Olaparib With or Without Bevacizumab in BRCA 1/2 Mutated or Homologous Recombination Deficient Ovarian Cancer

This study focuses on people with ovarian cancer who have tested positive for BRCA1/2 mutation (change or defect in the BRCA gene) or homologous recombination deficiency (when the body cannot repair breaks in DNA). The ...


Breast

Low-Dose Tamoxifen in Low-Risk, Early-Stage Breast Cancer

Hormone receptor-positive breast cancer is the most common type of breast cancer, and 5+ years of hormone therapy is the mainstay of the treatment. However, many patients experience side effects from the medications, and some ...


Other

A Long-Term Study of Elafibranor in Primary Biliary Cholangitis

The purpose of this study is to learn about the long-term benefits and side effects of repeated treatment for patients with primary biliary cholangitis (PBC) and cirrhosis. PBC occurs because of inflammation and injury of ...


Other

Siegel Transcatheter Aortic Valve Replacement System EFS Study

The purpose of this study is to determine whether an experimental device called the Siegel Transcatheter Aortic Valve Replacement (TAVR) System is safe and effective in treating adults who have aortic stenosis, a condition in ...