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390 results found


Melanoma, Unknown Sites

SWOG, S2101, PhII, open label, Cabozantinib + Nivolumab, Melanoma or HNSCC

Primary Objective: 1. To evaluate the feasibility of molecular characterization based on tumor mutation burden (TMB) for participant stratification, as assessed by the proportion of participants with less than or equal to a 21-day ...


Breast

Tart Cherry and Omega-3 s for Aromatase Inhibitor Musculoskeletal Symptoms

This study focuses on people with breast cancer who have aromatase therapy-associated musculoskeletal symptoms. The purpose of the study is to determine whether tart cherry concentrate and fish oil, when taken together, have an impact ...


Other

Comparison of Cardiac CT with TEE to Evaluate Watchman FLX LAA Occluder Device Characteristics

This study focuses on people who have atrial fibrillation and are scheduled for or underwent left atrial appendage closure (LAAC). The purpose of the study is to better understand differences between 2 ways of imaging ...


Obesity

Evaluating Environmental Control (AVOID) and Inhibitory Control (RESIST) Strategies to Improve Weight Management Outcomes

This study tests strategies to help adults with overweight or obesity (BMI between 25-45 kg/m2) “stick” to weight management recommendations. Specifically, the study evaluates the benefit of 2 self-regulatory approaches to improve intentional weight loss ...


Melanoma

Cemiplimab plus Ziv-Aflibercept in Metastatic Uveal Melanoma

The purpose of this phase II study for advanced melanoma is to evaluate the safety (side effects profile) and effectiveness (tumor shrinkage) of cemiplimab and ziv-aflibercept, when given together. Cemiplimab is an anti-cancer drug called ...