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Siegel Transcatheter Aortic Valve Replacement System EFS Study

The purpose of this study is to determine whether an experimental device called the Siegel Transcatheter Aortic Valve Replacement (TAVR) System is safe and effective in treating adults who have aortic stenosis, a condition in ...


Other

DMX-200 in Patients With Focal Segmental Glomerulosclerosis

This study will evaluate an experimental medication called DMX 200 (repagermanium) for people with focal segmental glomerulosclerosis (FSGS). FSGS is a progressive kidney disease in which the filters (glomeruli) of the kidneys become inflamed and ...


Lung

Amgen, 20230153, Ph 2, randomized, open-label, NSCLC, AMG193

Primary Objective: To characterize safety and efficacy of 2 dose levels of AMG 193 by investigator.


Esophagus, Larynx, Lip, Oral Cavity and Pharynx, Lung, Melanoma

Pfizer Inc, C5901001, Ph 1, Open-Label, Multi-Center, Melanoma, Solid Tumor, PF-08046031

Primary -To characterize the safety and tolerability profile of PF-08046031 in participants with advanced melanomas and select solid tumors (Parts 1, 2, 3) -To identify the MTD or MAD of PF-08046031 (Part 1) -To identify a recommended dose for ...


Leukemia, other

Venetoclax Plus Chemotherapy For Newly Diagnosed Acute Myeloid Leukemia

This study focuses on people who have a new diagnosis of acute myeloid leukemia (AML) who agreed to participate in the MyeloMATCH study and were matched to this treatment trial. The purpose of the study ...