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395 results found


Ovary

Ubamatamab in Platinum-Resistant Ovarian Cancer

The purpose of this study is to evaluate an investigational drug called ubamatamab in patients who have advanced ovarian cancer. Researchers want to determine how safe, tolerable, and effective ubamatamab is on its own and ...


Colon

Optimizing Body Weight With TCMCB07 in Patients With Newly Diagnosed Metastatic Colorectal Cancer Undergoing Chemotherapy

This study focuses on people with advanced colorectal cancer. The purpose of the study is to evaluate an experimental treatment called TCMB07 (B07) that may help cancer patients gain and/or maintain their weight while they ...


Other

Sirolimus-Coated Balloon Vs. Standard Balloon Angioplasty in Below-The-Knee Arterial Disease

The purpose of this study is to determine whether an experimental balloon device is effective in treating peripheral arterial disease (insufficient blood flow in the legs). The device, called Magic Touch PTA, is covered with ...


Unknown Sites

VS-7375 in Advanced KRAS G12D-Mutant Solid Tumors

This study focuses on people who have been diagnosed with a solid tumor that contains a specific change (mutation) in the KRAS gene. One common mutation in KRAS is called G12D; participants in this study ...


Unknown Sites

Zanzalintinib vs Everolimus in Locally Advanced or Metastatic Neuroendocrine Tumors

The purpose of this study is to evaluate the effectiveness of an experimental drug called zanzalintinib compared to the standard-of-care treatment, everolimus, in treating people with locally advanced or metastatic neuroendocrine tumors. Zanzalintinib is a ...