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Adjunctive Recombinant Human Plasma Gelsolin With Standard of Care for Moderate-to-Severe ARDS

The purpose of this study is to evaluate an experimental medication called gelsolin (recombinant human plasma gelsolin) in people who have moderate to severe acute respiratory distress syndrome (ARDS) due to pneumonia or other infections. ...


Tricuspid valve regurgitation

inQB8 MonarQ Transcatheter Tricuspid Valve Replacement System in Severe or Greater Tricuspid Regurgitation

This study focuses on people who were diagnosed with symptomatic severe tricuspid valve leakage. The purpose of this study is to learn whether an experimental device called the inQB8 MonarQ Transcatheter Tricuspid Valve Replacement (TTVR) ...


Other

Paclitaxel Coated Balloon for the Treatment of Chronic Benign Stricture- Esophagus

The purpose of this study is to assess the safety and effectiveness of an experimental device called the ProTractX3 TTS drug-coated balloon (DCB) for the treatment of benign (non-cancerous) stricture in the esophagus. A stricture ...


Other

Pegozafermin in Metabolic Dysfunction-Associated Steatohepatitis and Fibrosis

This study focuses on people who may have metabolic dysfunction-associated steatohepatitis (MASH), also called nonalcoholic steatohepatitis, that will be confirmed by a biopsy. The purpose of the study is to learn about the safety and ...


Prostate

Epigenetic Therapy Before Prostatectomy in Men With Prostate Cancer

This study focuses on people who have prostate cancer and are planning to have a radical prostatectomy (removal of prostate and some surrounding tissue). The purpose of the study is to assess the safety, tolerability, ...