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395 results found


Breast

PF-07220060 in Combination With Letrozole in HR-Positive, HER2-Negative Advanced/Metastatic Breast Cancer

This study focuses on people who have hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative, locally advanced or metastatic breast cancer and have not received any systemic anti-cancer treatment for their disease. The ...


Other

Quantification of Phosphorylated Alpha-Synuclein in Parkinson’s Disease and REM Sleep Behavior Disorder

The purpose of this study is to assess the ability of the Syn-One Test to measure the amount of phosphorylated alpha-synuclein (P-SYN) in skin biopsies from patients with Parkinson’s disease (PD) or rapid eye movement ...


Other

CoreAalst_P4 Study

To compare the rate of major adverse cardiovascular events between coronary CT angiography (CCTA)- and intravascular ultrasound (IVUS)-guided PCI strategies.


Other Female Genital

Sacituzumab Govitecan Versus Treatment of Physician’s Choice in Endometrial Cancer

The purpose of this study is to learn whether an experimental drug called sacituzumab govitecan (also called SG or Trodelvy) can help patients with endometrial cancer that has spread or recurred to live longer compared ...


Melanoma

PF-07799544 as a Single Agent and in Combination With Other Targeted Agents in BRAF-Mutant Melanoma and Other Solid Tumors

This study focuses on people who have melanoma (skin cancer) or other cancer with a specific change in the BRAF gene (BRAF alteration) and whose cancer has grown or spread. The study will explore the ...