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389 results found


Lung

Checkpoint Blockade in Lung Cancer Patients in the Adjuvant Setting

The purpose of this study is to compare the usual treatment alone (immune-based therapy with medications like durvalumab) to the usual treatment plus an experimental medication, AZD6738 (ceralasertib), in people with lung cancer who have ...


Other

Pulmocide_PC-ASP-006_OPERA-T Study

Primary Objective To assess the efficacy of nebulized PC945 in combination with systemic antifungal therapy for the treatment of refractory IPA Secondary Objective To assess the safety and tolerability of nebulized PC945 in combination with systemic antifungal therapy ...


Lung

Incorporating Pathologic Complete Response in Non-Small Cell Lung Cancer to Optimize Immunotherapy

The purpose of this study is to compare the usual approach of observation (closely watching a patient’s condition after surgery) to taking an immunotherapy drug, durvalumab (MEDI4736), in people with early-stage, non-small cell lung cancer ...


Other

CEREN-2

Primary -To evaluate the efficacy of itepekimab compared with placebo on NP size and nasal congestion Secondary - To evaluate the long-term efficacy of itepekimab compared with placebo on NP size. - To evaluate the long-term efficacy of itepekimab ...


Kidney

Alliance, A032201, Ph3, Rand, RCC, Pembrolizumab vs Pembrolizumab + Tivozanib

Primary Objective: 1. To compare disease free survival (DFS) as assessed by the investigator for high-risk renal cell carcinoma patients treated with adjuvant pembrolizumab and tivozanib versus those receiving pembrolizumab alone Secondary Objectives: 1. To compare overall survival ...