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CSMC, IIT2025-SALVY-AVOID-RESIST, Weight management

2.1 PRIMARY OBJECTIVE Aim 1 (Outcomes). (a) Tests how AVOID and RESIST affect weight loss (primary) and diet quality (secondary). H1a: AVOID and/or RESIST (arms, 2, 3, 4) will result in greater weight loss at 6-month ...


Melanoma

Phase 2, Multi-Center, MSK, Melanoma

Primary objectives: 1. Determine best ORR by RECIST v1.1 separately among patients whose melanoma progressed on prior anti-PD-1 monotherapy (Cohort A) and on anti-PD-1 and anti-LAG-3 ICI therapy (Cohort B) Secondary objectives: 1. Assess safety of fianlimab, cemiplimab, ...


Breast

CSMS, IIT2024-09-YUAN-NeoIVO, PhII, open-label, TNBC, Ivonescimab + Carboplatin + docetaxel

Primary Objective: Pathological complete response (pCR) rate Secondary Objectives: Event-free survival (EFS) Overall survival (OS) Patient-reported outcomes (PRO) Immune biomarkers