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392 results found


Prostate

Ifinatamab Deruxtecan Versus Docetaxel in Metastatic Castration-Resistant Prostate Cancer

The purpose of this study is to evaluate the safety and effectiveness of an experimental drug called ifinatamab deruxtecan (I-DXd) in treating people with metastatic castration-resistant prostate cancer (mCRPC), as compared to the standard-of-care treatment, ...


Anus, Breast, Lung, Other Female Genital, Ovary, Unknown Sites

Sumitomo Pharma America, Inc, SMP-3124-101, PhI/II, Open-label, SMP-3124LP, Solid tumors

Primary Objective: Dose Escalation: Determine the Recommended Phase 2 Dose (RP2D). Assess the safety and tolerability. Dose Expansion: Evaluate preliminary antitumor activity. Secondary Objectives: Dose Escalation: Establish the plasma PK profile of SMP-3124 and SMP-3124LP. Evaluate ...


Unknown Sites

BL-M07D1 in Subjects With HER2 Expressing Advanced Malignant Solid Tumors

The purpose of this study is to evaluate the safety, tolerability, and effectiveness of an experimental drug called BL-M07D1 as a possible treatment for people who have a type of advanced, inoperable cancer that expresses ...


Other

Boston Scientific Corporation_S2508_SIMPLAAFY

The primary objective is to demonstrate the safety and effectiveness of two monotherapy regimens versus dual antiplatelet (DAPT) therapy following implant with the WATCHMAN FLX Pro device.


Other

IONIS_ION582-CS2

Primary -To evaluate the efficacy of ION582 in participants with Angelman syndrome (AS) receiving ION582 vs Placebo as measured through expressive communication Secondary - To evaluate the efficacy of ION582 in participants with AS receiving ION582 vs Placebo ...