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Safety and Effectiveness of the TRBR Device in Breast Reconstruction

Primary endpoint Absence of device- or procedure-related major adverse events (MAEs) which require rehospitalization or reoperation through 1-year Post-Index Surgery (i.e., tissue expander implantation with or without the TRBR Device). Secondary endpoints ? BREAST-Q Physical Well Being, Chest ...


Anus, Breast, Colon, Liver, Lung, Pancreas, Prostate, Rectum

Phase I Study of DB-1317 in Selected Advanced/Metastatic Solid Tumors

The purpose of this Phase 1 study is to assess the safety and tolerability of an experimental drug called DB-1317 in patients with an advanced/metastatic (cancer that has spread from its original site) solid tumor ...


Other

Danicamtiv in Symptomatic Genetic and Familial Dilated Cardiomyopathy

The purpose of this study is to evaluate whether an experimental drug called danicamtiv improves heart function in adults with dilated cardiomyopathy compared to current standard treatment. DCM is a condition in which the heart ...


Anus, Breast, Cervix, Colon, Esophagus, Lip, Oral Cavity and Pharynx ...

DB-1311 in Combination With BNT327 or DB1305 in Advanced/Metastatic Solid Tumors

The purpose of this study is to evaluate the safety and tolerability of 2 experimental drug combinations in people who have been diagnosed with an advanced/metastatic (cancer that has spread from where it started) solid ...


Prostate

Xaluritamig vs Cabazitaxel or Second Androgen Receptor-Directed Therapy in Metastatic Prostate Cancer

The purpose of this study is to determine the safety and effectiveness of an experimental drug called xaluritamig when compared to standard treatments in people with prostate cancer that has spread to other parts of ...