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Tensi+ With Transcutaneous Tibial Nerve Stimulation for Overactive Bladder Syndrome

The purpose of this study is to evaluate the safety and effectiveness of the experimental Tensi+ device using transcutaneous posterior tibial nerve stimulation (TPTNS) for the treatment of patients with overactive bladder symptoms, such ...


Breast

BNT327 in Combination With Chemotherapy in Locally Recurrent, Inoperable or Metastatic TNBC

This study focuses on people who have triple-negative breast cancer (TNBC) that has metastasized to other organs and does not qualify for immunotherapy pembrolizumab treatment. The purpose of the study is to compare the effects ...


Other

LBBAP Versus CRT-D in Heart Failure, “SYNCHRONICITY”

This study focuses on people who have been diagnosed with heart failure and whose doctor has recommended that they receive an implant of a cardiac resynchronization therapy defibrillator (CRT-D), a type of medical device. The ...


Solid Tumors

PEEL-224 as a Single Agent and in Combination With Vincristine and Temozolomide

This study focuses on children who have a solid tumor that has come back (relapsed) or has not responded to standard treatments (refractory). The purpose of the study is to determine whether a drug called ...


Leukemia, other, Lymphoid Leukemia

Zanubrutinib Plus Sonrotoclax-Based Therapy Compared to Continuous Zanubrutinib in Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

This study focuses on people who have chronic lymphocytic leukemia or small lymphocytic lymphoma (CLL/SLL) that has never been treated before and whose disease has progressed to the point that therapy has been recommended. The ...