Find Clinical Trials | Cedars-Sinai

435 results found

Pancreas

ASP3082 in Combination With mFOLFIRINOX or NALIRIFOX in KRAS G12D-Mutated Metastatic Pancreatic Adenocarcinoma

The purpose of this study is to evaluate the safety and effectiveness of an experimental drug called ASP3082 in people who have metastatic pancreatic ductal adenocarcinoma cancer (PDAC) with a KRAS G12D mutation when combined ...

Pancreas

Daraxonrasib Vs. Standard-of-Care Observation in Resected Pancreatic Ductal Adenocarcinoma

The purpose of this study is to evaluate the safety, tolerability and effectiveness of an experimental drug called daraxonrasib (RMC-6236) in people with pancreatic cancer compared to standard-of-care treatment. Patients will be randomly assigned to ...

Urinary Bladder

Phase III Adaptive Radiation and Chemotherapy for Muscle Invasive Bladder Cancer Trial (ARCHER)

The purpose of this study is to compare radiation over a shorter timeframe plus chemotherapy to the usual radiation and chemotherapy in patients with muscle invasive bladder cancer (MIBC). Researchers aim to determine whether the ...

Kidney

Merck, MK-6482-033, Ph 3, Rand/open-label, RCC, Belzutifan+Zanzalintinib vz Cabozantinib

Primary Objective: To compare belzutifan + zanzalintinib to cabozantinib with respect to PFS per RECIST 1.1 as assessed by BICR To compare belzutifan + zanzalintinib to cabozantinib with respect to OS Secondary Objectives: To compare belzutifan + zanzalintinib to ...

Unknown Sites

Fianlimab Plus Cemiplimab Vs. Cemiplimab Plus Placebo in R/M Head and Neck Squamous Cell Carcinoma

The purpose of this study is to evaluate an experimental drug called fianlimab (REGN3767) alone or in combination with another drug called cemiplimab in people who have recurrent or metastatic head and neck cancer squamous ...