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433 results found


Pancreas

Astellas, 3082-CL-0301, Ph 3, Rand, Pancreatic Ca, ASP3082 vs placebo + mFolfirinox or NALIRIFOX

Primary Objective: - To compare the OS between participants treated with ASP3082 plus mFOLFIRINOX or NALIRIFOX vs placebo plus mFOLFIRINOX or NALIRIFOX Secondary Objectives: - To compare the PFS between participants treated with ASP3082 plus mFOLFIRINOX or NALIRIFOX vs placebo ...


Pancreas

Revolution Medicines, RMC-6236-304, Ph3, open/randomized, Pancreatic, Daraxonrasib

Primary Objective: To compare the effect of treatment with daraxonrasib following completion of neoadjuvant and/or adjuvant chemotherapy in patients with resected pancreatic ductal adenocarcinoma (PDAC) versus standard of care observation on Disease Free Survival (DFS) per ...


Urinary Bladder

NRG,NRG-GU015,Ph III,Rand,Bladder Ca,Chemo+Hypofractionation vs Chemo+(SBRT)ULTRAhypofractionation,

Primary Objective: Demonstrate non-inferiority of ultra-hypofractionated (stereotactic body radiation therapy [SBRT]) compared to hypofractionated radiation therapy (RT) with a 10% non-inferiority margin (from 50% to 40%) in the rate of bladder-intact event-free survival (BI-EFS) at ...