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439 results found


Breast

Rx Therapy Guided by Genomic Risk Assessment for ER-Pos/HER2-Neg Breast Cancer With RS≤25

The purpose of this study is to compare the usual treatment of chemotherapy followed by hormone therapy plus ribociclib to the study treatment of hormone therapy plus ribociclib. The study focuses on post-menopausal patients with ...


Other

Danicamtiv in Adults With Symptomatic Genetic and Familial Dilated Cardiomyopathy

This study focuses on people who have been diagnosed with dilated cardiomyopathy (DCM) and have completed participation in the DAN-301 (KINSHIP-DCM) study. The purpose of the study is to evaluate the long-term safety and effectiveness ...


Prostate

Alliance, A032304, Ph 3, randomized, prostate ca, 177Lu PSMA RLT standard vs adaptive schedule

Primary Objective: To compare the overall survival of patients with mCRPC receiving PSA adaptive dosing of 177Lu PSMA RLT to that of patients receiving standard dose 177Lu PSMA RLT Q6W To compare quality of life, ...


Lung

Alliance, A082302,Ph3,Rand,NSCLC,Obser vs Adjuvant Atezolizumab or Atezolizumab and Hyaluronidase-TQ

Primary Objective: To compare disease-free survival (DFS) in the intent-to-treat patient population, among patients randomized to receive atezolizumab for one year (Arm B) vs. observation (Arm A). DFS is defined as the time from randomization to the ...