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378 results found


Genetic Disorders of the Cardiovascular System, Heart failure

Cytokinetics (CK-3773274)

This study focuses on adults who have obstructive hypertrophic cardiomyopathy (oHCM), abnormally thick heart muscle, and left ventricular outflow tract (LVOT) obstruction (a condition which interferes with the flow of blood in the heart). The ...


Cardiac surgery

TRAVERSE: Transseptal vs Retrograde Aortic Ventricular Entry

The purpose of this study is to compare 2 methods that are each routinely performed as standards of care (a transseptal approach versus a retrograde approach) of performing a procedure, called ablation, to treat abnormal ...


Other

UVA Light Device to Treat COVID-19

To demonstrate basic safety and proof of principle for Endotracheal UV Light Device. Primary Endpoint: Reduction of viral load in upper airway in patients admitted to hospital positive for COVID-19. Secondary Endpoints: Overall reduction or change for the following ...


Urinary Bladder

BCG Prediction Assay, multiplex immunoassay for predicting intravesical BCG response

1.To examine the sensitivity and specificity of the multiplex immunoassay directed at a bladder cancer-associated signature in voided urine samples ability s to predict treatment response in patients with intermediate/high risk NMIBC treated with intravesical ...


Brain Injury

BOOST-3 NINDS Brain Oxygen Optimization

This study focuses on patients with severe traumatic brain injury (TBI). The purpose of the study is to compare two ways of treating patients with brain injury. Participants will be randomly assigned to one of ...