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156 results found


Prostate

Standard Systemic Therapy Vs. Standard Systemic Therapy Plus Definitive Treatment in Metastatic Prostate Cancer

The purpose of this study is to compare the effects of adding either prostate removal surgery or radiation therapy to standard systemic therapy for the treatment of metastatic prostate cancer. Researchers aim to determine whether ...


Small Intestine, Stomach

DRX-42 Versus Sunitinib in Metastatic and/or Unresectable Gastrointestinal Stromal Tumors After Imatinib Therapy

The purpose of this study is to determine the safety and effectiveness of an experimental drug called IDRX-42 compared to a drug called sunitinib (standard-of-care treatment) in people who have been diagnosed with advanced gastrointestinal ...


Breast

Reinvigorating Response To Immunotherapy in Triple-Negative Breast Cancer With Combination Myeloid Inhibition and Radiation

The purpose of this study is to evaluate the safety and effectiveness of a drug called pembrolizumab in combination with radiation therapy and another drug, axatilimab, in the treatment of patients with metastatic or locally ...


Lymphoid Leukemia

Lyell Immunopharma,LYL314-102, Ph3,rand,Rondecabtagene vs Inv choi, CarT-cell,Lg B-cell lymphoma

Primary Objectives: The primary endpoint of the study is to compare the efficacy of ronde-cel, an investigational CD19/CD20 CAR T-cell therapy, to the CD19 CAR T-cell therapies (axi-cel or liso-cel) based on EFS, defined as ...


Other Digestive Organ

Intraperitoneal Paclitaxel Plus Systemic Treatment Versus Systemic Treatment Alone in Gastric Carcinomatosis

This study focuses on people who have gastric cancer that has spread to the abdominal cavity. Researchers aim to determine whether they can lower the chance that the patient’s gastric cancer grows or spreads by ...