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147 results found


Leukemia, other

Venetoclax Plus Chemotherapy For Newly Diagnosed Acute Myeloid Leukemia

This study focuses on people who have a new diagnosis of acute myeloid leukemia (AML) who agreed to participate in the MyeloMATCH study and were matched to this treatment trial. The purpose of the study ...


Colon, Lung, Melanoma, Other Female Genital, Thyroid, Unknown Sites

Pierre Fabre Médicament, KN-8701/KIN2787CI101, Ph1/1b, open label, Solid Tumors, KIN-2787

2. Study Objectives 2.1. Part A Dose Escalation 2.1.1. Part A1: KIN-2787 Monotherapy Dose Escalation -The primary objectives of Part A1 are to determine the safety and tolerability of PO administration of KIN-2787 including DLTs in ...


Unknown Sites

Neoadjuvant Immunotherapy With Response-Adapted Treatment in Resectable Stage III/IV Cutaneous Squamous Cell Carcinoma

This study focuses on people who have advanced squamous cell skin cancer that can be removed with surgery. The purpose of the study is to determine whether giving an immunotherapy drug called cemiplimab before and ...


Other

Using Circulating Tumor DNA to Risk Adapt Post-Operative Therapy for HPV-Associated Oropharyngeal Cancer

The purpose of this study is to determine whether using less intense radiation therapy and chemotherapy (chemoradiation) after trans-oral robotic surgery (TORS) will be as effective in treating HPV-associated oropharyngeal cancer as standard treatment while ...


Unknown Sites

CSMC,IIT2023-08-ATKINS-ACCEL-RT, open, pilot, any histology/metastatic malignancy, ATHERO-RT

Primary Objective: To determine the feasibility of using 18F-NaF PET/MRI imaging for detection of real-time atherosclerosis activity in patients at high risk of RT-associated cardiac dysfunction. Secondary Objectives: To measure changes in standard uptake value (SUV) and coronary ...