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155 results found


Non-Hodgkin's Lymphoma

Nivolumab With Chemo-Immunotherapy for the Treatment of Primary Mediastinal B-Cell Lymphoma

This study focuses on individuals who have been diagnosed with primary mediastinal B Cell lymphoma (PMBCL). PMBCL is a type of cancer that occurs in the upper chest (in an area called the mediastinum). The ...


Kidney

HC-7366 in Combination With Belzutifan in Renal Cell Carcinoma

The purpose of this study is to evaluate the safety and effectiveness of an experimental drug called HC-7366 in combination with another drug, belzutifan (also known as MK-6482) in people who have inoperable or metastatic ...


Brain and Nervous System, Breast, Cervix, Colon, Lung, Other Female ...

Dragonfly Therapeutics, DF6215-001, Ph1/1B, Open, Solid Tumors, DF6215

Primary Objectives: Dose Escalation (Part 1) -To determine the maximum tolerated dose (MTD) of DF6215 Efficacy Expansion (Part 2) -To determine clinical activity of DF6215 Secondary Objectives: Dose Escalation (Part 1) -To assess the safety and tolerability of DF6215 Dose Escalation (Part 1) ...


Colon, Lung, Melanoma, Pancreas

Seagen, SGNBB228-001, Ph 1, Advanced Melanoma, Solid Tumors, SGN-BB228

Primary Objectives To evaluate the safety and tolerability of SGN-BB228 To identify the maximum tolerated dose (MTD) of SGN-BB228 (Part A) To identify a recommended dose and schedule for SGN-BB228 (Parts A ...


Multiple Myeloma

Alliance, A062102, Ph2, randomized, Multiple Myeloma, iberdomide vs observation

Primary Objective: To establish and confirm the safety and dose of iberdomide as maintenance after ide-cel CAR-T Secondary Objectives: Key secondary objective: To estimate the rate of conversion from MRD-positive at baseline to MRD-negative at any time ...