Find Clinical Trials | Cedars-Sinai

146 results found

Other Digestive Organ

Folfox in Combination with Binimetinib in Advanced Biliary Tract Cancers

This study focuses on individuals who have advanced biliary tract cancer and who may have had progression of cancer after previous treatments. The purpose of the study is to compare the usual treatment alone (chemotherapy ...

Bones and Joints, Breast, Cervix, Colon, Esophagus, Kidney, Liver, Lung ...

MacroGenics, Inc., CP-MGC026-01, Phase 1/1b, Open Label, Multi-Center, Solid Tumors, MGC026

Primary Objective: To characterize the safety, tolerability, dose-limiting toxicities (DLTs), and maximum tolerated dose (MTD) or maximum administered dose (MAD) (if no MTD is defined) of MGC026. Secondary Objective(s): To characterize the systemic pharmacokinetics (PK) of ...

Unknown Sites

ECOG, EAY191-E5, Ph2, Open label, Solid Tumors, AMG510(Sotorasib) +/- Panitumumab

Primary Objective: 1) To evaluate the efficacy of the combination of AMG 510 (Sotorasib) and panitumumab as compared to AMG 510 (Sotorasib) alone in patients with advanced/metastatic KRAS G12C mutated solid tumors (except CRC and NSCLC) as ...

Other Female Genital, Unknown Sites

Neratinib Alone or in Combination with Palbociclib in HER2+ Cancers and Other Solid Tumors

This study focuses on individuals who have recurrent or persistent cancer and whose cancer expresses a protein called HER2 (human growth factor receptor 2). The purpose of the study is to determine whether a combination ...

Unknown Sites

SWOG, EAY191-S3, Ph2, open label, Non-Breast Solid tumors, Ipatasertib + Paclitaxel

Primary Objective: To assess the overall response rate (ORR) (confirmed and unconfirmed, complete, and partial) with the combination of paclitaxel plus ipatasertib in participants with advanced AKT-altered non-breast solid tumors who have previously progressed on ...