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141 results found


Lung

Subcutaneous Amivantamab With Lazertinib or Subcutaneous Amivantamab With Chemotherapy in EGFR-Mutated Non-Small Cell Lung Cancer

This study focuses on people with non-small cell lung cancer (NSCLC) who have a specific mutation in a gene called the epidermal growth factor receptor (EFGR) gene. The purpose of the study is to learn ...


Other

Prevail Therapeutics_J3Z-MC-OJAE_LY3884961

Primary: To evaluate the safety and tolerability of LY3884961 Secondary: To evaluate the clinical and biomarker effects of LY3884961 on the following parameters, as outlined in the Schedule of Events: - Spleen volume - Platelet count - GluSph level ...


Eye and Orbit, Liver, Melanoma

Replimune, Inc, RP2-202, Randomized, Phase 2/3, Metastatic Uveal Melanoma,RP2, (IRB# 3812))

To compare the effect of RP2 + nivolumab relative to ipilimumab + nivolumab on progression free survival (PFS) Secondary Objectives To compare the effect of RP2 + nivolumab relative to ipilimumab + nivolumab on overall response ...


Leukemia, other

Venetoclax and HMA-based Therapies for Adults With FLT3-mutated Acute Myeloid Leukemia: A MyeloMATCH Treatment Trial

This study focuses on adults diagnosed with acute myeloid leukemia (AML) who have previously participated in another study called the myeloMATCH study. The purpose of this research is to compare the usual drug combination treatment ...


Esophagus, Stomach

Nivolumab + Paclitaxel + Ramucirumab in Advanced Gastric and Esophageal Adenocarcinoma

This study focuses on people who have advanced stomach or esophageal cancer that has spread. The purpose of the study is to compare the usual treatment alone (the combination of 2 drugs, paclitaxel and ramucirumab) ...