Find Clinical Trials | Cedars-Sinai

151 results found

Kidney

Risk-Adapted Treatment of Unilateral Favorable Histology Wilms Tumors

The purpose of this study is to improve outcomes for children with a diagnosis of favorable histology Wilms tumor (FHWT), a cancer type in which certain microscopic characteristics of tumor cells are associated with a ...

Breast

Belzutifan Plus Fulvestrant in ER-Positive, HER2-Negative Unresectable Locally Advanced or Metastatic Breast Cancer

This study focuses on people who have been diagnosed with estrogen receptor-positive (ER+)/HER2-negative breast cancer that cannot be removed surgically, has come back, or has spread to other areas of the body, and/or has grown ...

Prostate

CSMC, IIT2023-10-Posadas-PC-NET, open-label, pilot, Prostate Ca, epigenetic therapy + prostatectomy

Primary Objective: 1. To assess the safety, toxicity, and feasibility of using epigenetic therapy in the perioperative setting for men undergoing radical prostatectomy (RP). 2. To assess the feasibility of measuring changes in gene expression (in radical ...

Breast

Pfizer, C4391024, Ph3, Open-label, randomized, Br CA, PF-07220060+Letrozole vs CDK4/6+ Letrozole

Primary Objective: To compare the efficacy of PF07220060 in combination with letrozole (Arm A) versus CDK4/6i (investigator s choice: abemaciclib, palbociclib, or ribociclib) in combination with letrozole (Arm B) with respect to progression-free survival (PFS). Secondary Objectives: To ...

Other Female Genital

Gilead/GOG, GS-US-682-6769/GOG-3104, Ph 3, open,Sacituzumab Govitecan vs TPC,Endometrial CA

Primary: To compare the effect of sacituzumab govitecan (SG) relative to treatment of physician s choice (TPC) on progression-free survival (PFS) as assessed by blinded independent central review (BICR) To compare the effect of SG relative to ...