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150 results found


Cervix, Kidney, Lung, Other Female Genital, Pancreas, Rectum, Small Intestine

KO-2806 in Adult Patients With Advanced Solid Tumors

The purpose of this study is to determine the highest tolerable dose of an investigational drug called KO-2806 in combination with an approved therapy called cabozantinib, in people with renal cell carcinoma (RCC) of predominantly ...


Unknown Sites

Newly Diagnosed Very Low-risk and Low-Risk Fusion Negative Rhabdomyosarcoma

This study focuses on people who have been diagnosed with rhabdomyosarcoma (RMS), a type of cancer that occurs in the soft tissues of the body and whose cancer is considered low-risk (LR-RMS). The purpose of ...


Prostate

High Five Trial: High-Risk Prostate Cancer

The purpose of this study is to compare 2 radiation schedules that can be used to treat patients with high-risk prostate cancer. One approach delivers a higher dose of radiation per treatment and uses fewer ...


Prostate

CSMC, IIT2022-16-Freedland-URO-PRO, Ph2, blinded, prostate cancer, Urolithin A vs. placebo

1.1 Primary Objectives The primary objective of this study is to determine the effect of a 3-to-6-week intervention of Urolithin-A (Uro-A) supplements versus placebo on 8-OHdG percent positive change in prostate cancer tumor tissue obtained by ...


Lymphoid Leukemia

SWOG,MM1YA-S01,Ph2,rand/open label, AML,Cytarabine,Daunorubicin,venetoclax,azacitidine

Primary Objective: To compare measurable residual disease (MRD) negative complete remission (CR) rates between each of the experimental regimens and Cytarabine + Daunorubicin (7+3). Secondary Objectives: a. To estimate the frequency and severity of toxicities with each of ...