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140 results found


Melanoma

ALKS 4230 as Monotherapy in Advanced Melanoma

The purpose of this study is to evaluate the effectiveness, safety, and tolerability of an experimental drug called nemvaleukin (modified interleukin-2, improves immune function towards melanoma) in people with melanoma. The study focuses on individuals ...


Breast, Colon, Other Skin, Ovary, Pancreas, Prostate

Agenus Inc, C-800-01, Ph1, open, Adv Solid Tumors, 3wk/6wk AGEN1181 alone / 6wk AGEN1181+AGEN2034

This study focuses on individuals who have solid tumors that are locally advanced or that has spread to new areas of the body for which no standard therapy is available, or standard therapy has failed. ...


Brain and Nervous System

Identification of Pre-Malignant Lesions In Pediatric Patients With Neurofibromatosis Type 1

The purpose of this study is to evaluate the use of a magnetic resonance imaging (MRI) technique called whole-body MRI, combined with a computer program, in children and adolescents (5-18 years old) with neurofibromatosis type ...


Brain and Nervous System

BPM31510 With Vitamin K1 in Newly Diagnosed Glioblastoma

This study focuses on individuals who have recently been diagnosed with glioblastoma (GB), a type of brain cancer. The purpose of the study is to evaluate the safety and effectiveness of BPM31510 (an experimental drug) ...


Prostate

Evaluating De-Intensification for Lower Genomic Risk and Intensification of Concurrent Therapy for Higher Genomic Risk With Radiation in Prostate Cancer

This study is using a new test that provides a gene risk score to more precisely separate high-risk prostate cancer patients into risk groups that can then guide treatment decisions. For patients with a lower ...