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146 results found


Breast

Da Vinci SP Surgical System in Nipple-Sparing Mastectomy

The purpose of this clinical study is to collect data about the use of a robotic device called the da Vinci Single-Port (SP) Surgical System in nipple-sparing mastectomy (NSM) procedures. NSM is a surgery for ...


Hodgkin's Lymphoma, Leukemia, not otherwise specified, Leukemia, other, Lymphoid Leukemia ...

Post-Transplant Cyclophosphamide

The purpose of this study is to determine the best dose of an immune suppressive drug, cyclophosphamide, following standard stem cell transplant in older patients (at least 65 years old). Participants will undergo a stem ...


Lung, Rectum

HPN328 in Advanced Cancers Associated with DLL3

The purpose of this study is to test the safety and effects of an experimental drug called HPN328 alone and in combination with another drug, atezolizumab, in patients who have small cell lung cancer or ...


Breast

Shorter Anthracycline-Free Chemo Immunotherapy in Early Triple-Negative Breast Cancer

The purpose of this study is to compare the standard-of-care chemo-immunotherapy (carboplatin/paclitaxel followed by adriamycin/cyclophosphamide plus pembrolizumab, given in 6 months) treatment for early-stage, triple-negative breast cancer to a shorter non-anthracycline chemo-immunotherapy treatment (carboplatin docetaxel ...


Breast, Cervix, Colon, Esophagus, Kidney, Liver, Lung, Melanoma, Other Female ...

GIM-122 as a Single Agent in Advanced Solid Malignancies

The purpose of this study is to evaluate an investigational drug called GIM-122 in people who have been diagnosed with an advanced or malignant tumors. These patients have tumors that were eligible to be treated ...