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140 results found


Lung

Ramucirumab plus Pembrolizumab Versus Standard of Care for Stage IV or Recurrent Non-Small Cell Lung Cancer

This study aims to determine whether a new combination of 2 non-chemotherapy drugs can help patients with advanced non-small cell lung cancer to live longer than the usual approach. (The usual approach is defined as ...


Melanoma

Sarilumab Combined With Ipilimumab, Nivolumab, and Relatlimab in Advanced/Unresectable Melanoma

This study will evaluate the safety and tolerability of a drug called sarilumab in combination with ipilimumab, nivolumab, and relatlimab in advanced/unresectable melanoma (melanoma that cannot be removed by surgery). Ipilimumab, nivolumab, and relatlimab ...


Multiple Myeloma

Elranatamab in Combination With Other Anti-Cancer Treatments in Multiple Myeloma

The purpose of the study is to learn whether an investigational drug called nirogacestat can improve the effectiveness of another drug, elranatamab, in treating patients with multiple myeloma who have had their disease relapse. Elranatamab is ...


Prostate

Apalutamide With Carotuximab in Metastatic, Castration-Resistant Prostate Cancer

This study will evaluate an experimental drug called carotuximab when taken in combination with apalutamide, in comparison to apalutamide alone, for the treatment of metastatic, castration-resistant prostate cancer. Carotuximab is a genetically engineered antibody (type ...


Breast cancer

T-DM1 and Placebo Compared With T-DM1 AND Tucatinib in HER2-Positive Breast Cancer

This study focuses on patients who have human epidermal growth factor receptor 2 (HER2)-positive breast cancer and who have already received treatment with chemotherapy and anti-HER2 targeted therapies followed by surgery. The study will evaluate ...