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165 results found


Non-Hodgkin Lymphoma, Other Hematopoietic

Cemacabtagene Ansegedleucel in Large B-Cell Lymphoma

This study focuses on individuals with large B-cell lymphoma who have completed initial therapy. The study aims to determine whether CAR T cells made from healthy donors are an effective treatment to prevent relapse in ...


Anus, Bones and Joints, Brain and Nervous System, Breast, Cervix ...

Molecular Analysis for Combination Therapy Choice (ComboMATCH)

The purpose of this study is to identify patients based on gene changes or mutations in their tumor for treatment using a combination of targeted therapy. The study focuses on patients who have had a ...


Cervix

NRG, NRG-GY032, Ph2,Open-Label, Early Stage Endometrial Cancer, De-escalated adjuv or observation

Primary Objective Estimate the rate of pelvic recurrence at 3 years in patients who are treated with a de-escalated adjuvant treatment directed by tumor molecular status. Secondary Objectives Estimate the rate of isolated vaginal recurrence, para-aortic ...


Lymphoid Leukemia, Non-Hodgkin Lymphoma

Comparing Rituximab and Mosunetuzumab in Low Tumor Burden Follicular Lymphoma

The purpose of this study is to compare the usual treatment (rituximab) to an experimental drug called mosunetuzumab in people with low tumor burden follicular lymphoma. Mosunetuzumab is a type of drug known as a ...


Bones and Joints, Breast, Cervix, Colon, Esophagus, Kidney, Liver, Lung ...

MacroGenics, Inc., CP-MGC026-01, Phase 1/1b, Open Label, Multi-Center, Solid Tumors, MGC026

Primary Objective: To characterize the safety, tolerability, dose-limiting toxicities (DLTs), and maximum tolerated dose (MTD) or maximum administered dose (MAD) (if no MTD is defined) of MGC026. Secondary Objective(s): To characterize the systemic pharmacokinetics (PK) of ...