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162 results found


Melanoma

GIM-531 as a Single Agent and in Combination With Anti-PD-1 in Advanced Solid Tumors

This study focuses on individuals who have been diagnosed with advanced stage cancer. The purpose of the study is to determine whether an experimental drug called GIM-531 is safe and can help the immune system ...


Melanoma

OBX-115 in Unresectable or Metastatic Melanoma

The goal of this study is to determine the recommended dose of an experimental cell therapy called OBX-115 with another medication called acetazolamide (approved by the U.S. Food and Drug Administration as a mild diuretic) ...


Melanoma

Vusolimogene Oderparepvec in Combination With Nivolumab in Advanced Melanoma

The purpose of this study is to evaluate an experimental drug called vusolimogene oderparepvec (VO) in combination with another drug, nivolumab, in people who have advanced melanoma. Researchers will compare the effects of nivolumab with ...


Non-Hodgkin Lymphoma, Other Hematopoietic

Cemacabtagene Ansegedleucel in Large B-Cell Lymphoma

This study focuses on individuals with large B-cell lymphoma who have completed initial therapy. The study aims to determine whether CAR T cells made from healthy donors are an effective treatment to prevent relapse in ...


Anus, Bones and Joints, Brain and Nervous System, Breast, Cervix ...

Molecular Analysis for Combination Therapy Choice (ComboMATCH)

The purpose of this study is to identify patients based on gene changes or mutations in their tumor for treatment using a combination of targeted therapy. The study focuses on patients who have had a ...