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158 results found


Melanoma

IMC-F106C Plus Nivolumab Versus Nivolumab Regimens in Advanced Melanoma

This study focuses on adults with advanced melanoma (a type of skin cancer) that has spread or cannot be surgically removed. The purpose of the study is to determine whether an experimental drug called IMC-F106C, ...


Multiple Myeloma

Iberdomide Maintenance Therapy Following CAR-T in Multiple Myeloma

This study focuses on individuals who have multiple myeloma that has relapsed (meaning it has come back after prior therapy) and/or refractory (resistant to certain therapies). The purpose of the study is to determine whether ...


Non-Hodgkin's Lymphoma

IPH6501 in Relapsed and/or Refractory Non-Hodgkin Lymphoma

The purpose of this study is to determine the safety and tolerability of an experimental drug called IPH6501, as well as evaluate its activity against cancerous cells causing lymphoma. The study focuses on people who ...


Multiple Myeloma

Janssen Scientific Affairs, LLC, 68284528MMY4006, EAP, openl,MM, ciltacabtagene autoleucel OOS,

Primary Objective: The purpose of this expanded access program (EAP) is to provide ciltacabtagene autoleucel (cilta-cel) that does not meet the commercial release specifications of CARVYKTI and is not available via the local health care ...


Lymphoid Leukemia

Genmab, GCT3013-03, Ph 1/2b, Open-Label, GEN3013, Leukemia/Richter's Syndrome

Objectives and Endpoints: Dose Escalation Monotherapy Cohorts (R/R CLL): Primary Objective: Identify the RP2D and the MTD of epcoritamab Evaluate the safety and tolerability of epcoritamab Secondary: Characterize the PK properties of epcoritamab Evaluate immunogenicity of epcoritamab Assess the preliminary antitumor activity ...