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161 results found

Anus, Breast, Cervix, Colon, Corpus Uteri, Hodgkin's Lymphoma, Kidney, Liver ...

RGX-104 in Advanced Solid Malignancies and Lymphoma

This study focuses on patients with advanced cancer for which further treatment is recommended, but standard (“non-research”) treatment is no longer effective. The study will evaluate RGX-104, an investigational drug that binds to proteins. It ...

Breast cancer

Immune Checkpoint Inhibition with Pembrolizumab + PARP Inhibition With Olaparib in Breast Cancer

The purpose of this study is to evaluate the investigational use of 2 drugs, pembrolizumab and olaparib, on patients with advanced BRCA-mutated or HDR-defect breast cancer that has progressed (worsened) after previous treatment. BRCA1 and ...

Pancreatic Biliary Diseases, Pancreatic Diseases

Prospective Evaluation of Chronic Pancreatitis

The purpose of this study is to gain knowledge about chronic pancreatitis and discover new ways to detect, treat, and help prevent the disease. Chronic pancreatitis occurs when the pancreas is affected by inflammation and ...

Disease-free, Ovary

Health Care Outcomes Following Risk-Reducing Salpingo-Oophorectomy

The purpose of this study is to evaluate the long-term effect of risk-reducing, bilateral salpingo-oophorectomy (removal of fallopian tubes and ovaries) on health outcomes in women with genetic mutations known to increase the risk for ...


Hispanic Colorectal Cancer Study

The purpose of the Hispanic Colorectal Cancer Study (HCCS) is to improve understanding of colorectal cancer in Hispanics/Latinos. The study aims are to identify various factors that may increase the chance of developing colorectal cancer, ...