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140 results found


Breast, Esophagus, Larynx, Lip, Oral Cavity and Pharynx, Lung, Melanoma ...

INCA33890 in Advanced or Metastatic Solid Tumors

The purpose of this study is to determine the safest and most effective dose of an experimental drug called INCA33890 in people with selected advanced or metastatic solid tumors. INCA33890 is an immune therapy (drug ...


Other Hematopoietic

Zanubrutinib in Mantle Cell Lymphoma

This study focuses on individuals who have mantle cell lymphoma, which is a type of non-Hodgkin lymphoma. Zanubrutib is a drug approved by the U.S. Food and Drug Administration (FDA) for use in mantle cell ...


Bones and Joints, Breast, Cervix, Colon, Kidney, Liver, Lung, Melanoma ...

PARG Inhibitor IDE161 in Advanced Solid Tumors

This study focuses on individuals who have a solid tumor cancer (not a blood cancer) that has worsened and has not responded to at least one prior cancer treatment. The purpose of the study is ...


Brain and Nervous System

TVI-BRAIN-1 Combined With Conformal Radiotherapy and Temozolomide as Treatment for Glioblastoma

The purpose of this study is to determine the safety and effectiveness of an experimental immunotherapy called TVI-Brain-1 for the treatment of newly diagnosed glioblastomas (a form of brain cancer) when combined with standard-of-care surgery, ...


Non-Hodgkin's Lymphoma

IMPT-314 in Aggressive B-Cell Non-Hodgkin Lymphoma

The purpose of this study is to evaluate experimental gene-modified immune cells called IMPT-314 for the treatment of lymphomas that have either come back after treatment or have stopped responding to treatment. IMPT-314 is a ...