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163 results found


Breast

Bria-IMT Regimen With Check Point Inhibitor vs Physician’s Choice in Metastatic Breast Cancer

The purpose of this study is to assess the safety and effectiveness of an experimental therapy for advanced breast cancer called Bria-IMT (SV-BR-1-GM) cancer vaccine in combination with immune checkpoint inhibitor retifanlimab. Retifanlimab can help ...


Lung

BNT324 with BNT327 in Participants With Advanced Lung Cancer

The purpose of this study is to assess whether the investigational drugs BNT324 and BNT327 can help control advanced or metastatic lung cancer. The study aims to determine the most suitable combination dose of BNT324 ...


Urinary Bladder

Bladder Preservation with Immunoradiotherapy in Muscle Invasive Bladder Cancer

This study focuses on people who have responded to chemotherapy or chemotherapy-like treatment for muscle invasive bladder cancer, and the cancer has either shrunk or cannot be found. The purpose of the study is to ...


Lymphoid Leukemia, Non-Hodgkin Lymphoma

Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid in Diffuse-Large B-Cell Lymphoma and High-Grade B-Cell Lymphoma

The purpose of this study is to determine whether treatment with ViPOR (a combination of the drugs venetoclax, ibrutinib, prednisone, obinutuzumab, and lenalidomide) will lead to disappearance of all sites of cancer (i.e., complete remission) ...


Gynecologic Cancer, Ovarian cancer

Ubamatamab in Platinum-Resistant Ovarian Cancer

The purpose of this study is to evaluate an investigational drug called ubamatamab in patients who have advanced ovarian cancer. Researchers want to determine how safe, tolerable, and effective ubamatamab is on its own and ...