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156 results found


Breast

Belzutifan Plus Fulvestrant in ER-Positive, HER2-Negative Unresectable Locally Advanced or Metastatic Breast Cancer

This study focuses on people who have been diagnosed with estrogen receptor-positive (ER+)/HER2-negative breast cancer that cannot be removed surgically, has come back, or has spread to other areas of the body, and/or has grown ...


Prostate

Epigenetic Therapy Before Prostatectomy in Men With Prostate Cancer

This study focuses on people who have prostate cancer and are planning to have a radical prostatectomy (removal of prostate and some surrounding tissue). The purpose of the study is to assess the safety, tolerability, ...


Melanoma

PF-07799544 as a Single Agent and in Combination With Other Targeted Agents in BRAF-Mutant Melanoma and Other Solid Tumors

This study focuses on people who have melanoma (skin cancer) or other cancer with a specific change in the BRAF gene (BRAF alteration) and whose cancer has grown or spread. The study will explore the ...


Non-Hodgkin's Lymphoma, Other Hematopoietic

MK-2140 in Combination With R-CHP Versus R-CHOP in Diffuse Large B-Cell Lymphoma

The purpose of this study is to evaluate the safety and effectiveness of the combination of an experimental drug called zilovertamab vedotin (MK-2140) plus a series of cancer drugs (R-CHP) in treating people with diffuse ...


Melanoma

Regeneron, R3767-ONC-2466, Ph2, open label, Melanoma, Fianlimab Plus Cemiplimab

Primary -Assess Overall Survival (OS) of patients with melanoma treated with Fianlimab Plus Cemiplimab in Expansion Cohorts from R3767-ONC-1613 Secondary -Assess Progression-Free Survival (PFS) -Assess Objective Response Rate (ORR) -Assess Duration of Response (DOR) -Assess Disease Control Rate (DCR) ...