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153 results found


Multiple Myeloma

ABBV-383 Compared With Standard Available Therapies in Relapsed or Refractory Multiple Myeloma

The purpose of this study is to evaluate the safety and effectiveness of an experimental drug called ABBV-383 in people with relapsed or refractory multiple myeloma (multiple myeloma that has come back or did not ...


Lung

Merck,MK-2870-019, Ph3, Open label randomized, Pembrolizumab +/- MK-2870 , NSCLC

Primary Objective: Objective: To compare MK-2870 plus pembrolizumab versus pembrolizumab monotherapy with respect to DFS as assessed by BICR. DFS: the time from randomization to any recurrence (local, locoregional, regional or distant), occurrence of new primary NSCLC, or ...


Lymphoid Leukemia

AZD0486 in Adolescents and Adults With Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia

The purpose of this study is to learn more about an experimental drug called AZD0486 and determine whether it will be safe, tolerable, and effective in treating B-cell acute lymphoblastic leukemia (B-ALL). AZD0486 is ...


Breast, Kidney, Lung, Multiple Myeloma, Other Digestive Organ, Ovary, Pancreas ...

QXL138AM in Locally Advanced Unresectable and/or Metastatic Solid Tumors and Multiple Myeloma

The purpose of this study is to evaluate the safety and tolerability of an experimental drug called QXL138AM in people with advanced solid tumors and multiple myeloma. There are 2 parts to this study. In ...


Urinary Bladder

Bladder Preservation for Patients With Muscle Invasive Bladder Cancer With Variant Histology

The goal of this study is to evaluate a treatment called trimodal therapy after a course of neoadjuvant therapy (treatment given as a first step to shrink a tumor before main treatment) as a way ...