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151 results found


Melanoma

Vusolimogene Oderparepvec in Combination With Nivolumab in Advanced Melanoma

The purpose of this study is to evaluate an experimental drug called vusolimogene oderparepvec (VO) in combination with another drug, nivolumab, in people who have advanced melanoma. Researchers will compare the effects of nivolumab with ...


Other Hematopoietic

Cemacabtagene Ansegedleucel in Large B-Cell Lymphoma

This study focuses on individuals with large B-cell lymphoma who have completed initial therapy. The study aims to determine whether CAR T cells made from healthy donors are an effective treatment to prevent relapse in ...


Colon, Lip, Oral Cavity and Pharynx, Melanoma, Pancreas

IPN01194 as Single Agent in Advanced Solid Tumors

The purpose of this study is to evaluate an experimental drug called IPN01194 in people with selected mutations in advanced solid cancers. IPN01194 is a small molecule targeting a pathway called MAPK, which is frequently ...


Anus, Bones and Joints, Brain and Nervous System, Breast, Cervix ...

Molecular Analysis for Combination Therapy Choice (ComboMATCH)

The purpose of this study is to identify patients based on gene changes or mutations in their tumor for treatment using a combination of targeted therapy. The study focuses on patients who have had a ...


Cervix

NRG, NRG-GY032, Ph2,Open-Label, Early Stage Endometrial Cancer, De-escalated adjuv or observation

Primary Objective Estimate the rate of pelvic recurrence at 3 years in patients who are treated with a de-escalated adjuvant treatment directed by tumor molecular status. Secondary Objectives Estimate the rate of isolated vaginal recurrence, para-aortic ...