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156 results found

Solid Tumors

Bristol-Myers Squibb, CA2360001, Ph 1/2, Open-Label, Multi-center, NSCLC, BMS-986482, Solid Tumor

Primary : To assess the safety and tolerability of oral BMS-986482, as monotherapy or in combination with nivolumab SC, nivolumab + relatlimab FDC SC, or bevacizumab, to establish the MTD,MAD, and/or RP2D(s) in participants with advanced solid ...

Liver

SIRT with Tremelimumab and Durvalumab for Resectable Hepatocellular Carcinoma

This study focuses on people who have liver cancer (hepatocellular carcinoma-HCC) for which they will be undergoing surgical treatment. The purpose of the study is to evaluate the safety and tolerability of neoadjuvant treatment (treatment ...

Lung

Incorporating Pathologic Complete Response in Non-Small Cell Lung Cancer to Optimize Immunotherapy

The purpose of this study is to compare the usual approach of observation (closely watching a patient’s condition after surgery) to taking an immunotherapy drug, durvalumab (MEDI4736), in people with early-stage, non-small cell lung cancer ...

Kidney

Short-Term Intensified Pembrolizumab and Tivozanib for High-Risk Renal Cell Carcinoma

The purpose of this study is to evaluate whether the addition of a drug called tivozanib to another drug, pembrolizumab, is better than the usual approach (pembrolizumab alone) for treating advanced kidney cancer. Specifically, researchers ...

Prostate

Ifinatamab Deruxtecan Versus Docetaxel in Metastatic Castration-Resistant Prostate Cancer

The purpose of this study is to evaluate the safety and effectiveness of an experimental drug called ifinatamab deruxtecan (I-DXd) in treating people with metastatic castration-resistant prostate cancer (mCRPC), as compared to the standard-of-care treatment, ...