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153 results found


Lung

Harpoon Therapeutics, HPN328-4001, Ph 1/2, OL, advanced SCLC/tumors with expression of DLL3, HPN328

Primary Objectives -Assess safety and tolerability at increasing dose levels of HPN328 in successive cohorts of patients with solid tumors associated with expression of DLL3 -Estimate the maximum tolerated dose (MTD) or select the recommended Phase 2 ...


Breast

Shorter Anthracycline-Free Chemo Immunotherapy in Early Triple-Negative Breast Cancer

The purpose of this study is to compare the standard-of-care chemo-immunotherapy (carboplatin/paclitaxel followed by adriamycin/cyclophosphamide plus pembrolizumab, given in 6 months) treatment for early-stage, triple-negative breast cancer to a shorter non-anthracycline chemo-immunotherapy treatment (carboplatin docetaxel ...


Breast, Cervix, Esophagus, Kidney, Larynx, Liver, Lung, Other Digestive Organ ...

BMS-986449 Alone and in Combination with Nivolumab in Advanced Solid Tumors

This study will evaluate the safety and side effects of an investigational drug called BMS-986449 in patients with an advanced solid tumor that has grown or come back. The study also aims to determine the ...


Breast, Cervix, Colon, Esophagus, Kidney, Liver, Lung, Melanoma, Other Female ...

GIM-122 as a Single Agent in Advanced Solid Malignancies

The purpose of this study is to evaluate an investigational drug called GIM-122 in people who have been diagnosed with an advanced or malignant tumors. These patients have tumors that were eligible to be treated ...


Colon, Rectum

Personalized Self-Management Training Compared to Standardized Self-Management Training in Colorectal Cancer

The purpose of this study is to examine the effectiveness and patient experiences of colorectal cancer survivors who complete a 6-week, personalized self-management training program called RISE compared to a standardized self-management training program. Researchers ...