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140 results found


Myeloid and Monocytic Leukemia

MYELOMATCH, Master Screening and Reassessment Protocol

In this study, researchers will plan various treatment substudies for people with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) who have not yet started treatment. Participants will be asked to undergo testing on their ...


Unknown Sites

Dinutuximab Added to Intensive Multimodal Therapy for Children with Neuroblastoma

The purpose of this study is to compare the outcomes of a drug called dinutuximab, given early with induction therapy, to the effects of standard induction therapy with the addition of dinutuximab later in therapy, ...


Cervix, Kidney, Lung, Other Female Genital, Pancreas, Rectum, Small Intestine

KO-2806 in Adult Patients With Advanced Solid Tumors

The purpose of this study is to determine the highest tolerable dose of an investigational drug called KO-2806 in combination with an approved therapy called cabozantinib, in people with renal cell carcinoma (RCC) of predominantly ...


Unknown Sites

Newly Diagnosed Very Low-risk and Low-Risk Fusion Negative Rhabdomyosarcoma

This study focuses on people who have been diagnosed with rhabdomyosarcoma (RMS), a type of cancer that occurs in the soft tissues of the body and whose cancer is considered low-risk (LR-RMS). The purpose of ...


Prostate

High Five Trial: High-Risk Prostate Cancer

The purpose of this study is to compare 2 radiation schedules that can be used to treat patients with high-risk prostate cancer. One approach delivers a higher dose of radiation per treatment and uses fewer ...