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158 results found


Ovary

Olaparib With or Without Bevacizumab in BRCA 1/2 Mutated or Homologous Recombination Deficient Ovarian Cancer

This study focuses on people with ovarian cancer who have tested positive for BRCA1/2 mutation (change or defect in the BRCA gene) or homologous recombination deficiency (when the body cannot repair breaks in DNA). The ...


Breast

Low-Dose Tamoxifen in Low-Risk, Early-Stage Breast Cancer

Hormone receptor-positive breast cancer is the most common type of breast cancer, and 5+ years of hormone therapy is the mainstay of the treatment. However, many patients experience side effects from the medications, and some ...


Lung

Amgen, 20230153, Ph 2, randomized, open-label, NSCLC, AMG193

Primary Objective: To characterize safety and efficacy of 2 dose levels of AMG 193 by investigator.


Esophagus, Larynx, Lip, Oral Cavity and Pharynx, Lung, Melanoma

Safety and Effects of PF-08046031 in Advanced Melanoma and Other Solid Tumors

This clinical trial is for adults with advanced melanoma or certain other types of solid tumors. The goal is to learn more about a new investigational drug called PF-08046031, including how safe it is, how ...


Leukemia, other

Venetoclax Plus Chemotherapy For Newly Diagnosed Acute Myeloid Leukemia

This study focuses on people who have a new diagnosis of acute myeloid leukemia (AML) who agreed to participate in the MyeloMATCH study and were matched to this treatment trial. The purpose of the study ...