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155 results found

Bones and Joints, Breast, Cervix, Colon, Kidney, Liver, Lung, Melanoma ...

PARG Inhibitor IDE161 in Advanced Solid Tumors

This study focuses on individuals who have a solid tumor cancer (not a blood cancer) that has worsened and has not responded to at least one prior cancer treatment. The purpose of the study is ...

Other Hematopoietic

Addition of Targeted Therapeutic Agents to Tafasitamab-Based Therapy in Large B-Cell Lymphoma

This study focuses on patients with relapsed or refractory large b-cell lymphoma (LBCL). Relapsed means the LBCL has returned after it responded to treatment; refractory means the LBCL did not respond to earlier treatment. The ...

Brain and Nervous System

TVI-BRAIN-1 Combined With Conformal Radiotherapy and Temozolomide as Treatment for Glioblastoma

The purpose of this study is to determine the safety and effectiveness of an experimental immunotherapy called TVI-Brain-1 for the treatment of newly diagnosed glioblastomas (a form of brain cancer) when combined with standard-of-care surgery, ...

Non-Hodgkin's Lymphoma

IMPT-314 in Aggressive B-Cell Non-Hodgkin Lymphoma

The purpose of this study is to evaluate experimental gene-modified immune cells called IMPT-314 for the treatment of lymphomas that have either come back after treatment or have stopped responding to treatment. IMPT-314 is a ...

Anus, Brain and Nervous System, Breast, Cervix, Colon, Esophagus

LCB84 as a Single Agent and in Combination With Pembrolizumab in Advanced Solid Tumors

This study focuses on individuals who have metastatic cancer (cancer that has spread) that has not responded to standard treatments or for whom no effective therapy is available. The purpose of the study is to ...