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163 results found


Anus, Breast, Colon, Liver, Lung, Pancreas, Prostate, Rectum

Phase I Study of DB-1317 in Selected Advanced/Metastatic Solid Tumors

The purpose of this Phase 1 study is to assess the safety and tolerability of an experimental drug called DB-1317 in patients with an advanced/metastatic (cancer that has spread from its original site) solid tumor ...


Anus, Breast, Cervix, Colon, Esophagus, Lip, Oral Cavity and Pharynx ...

DB-1311 in Combination With BNT327 or DB1305 in Advanced/Metastatic Solid Tumors

The purpose of this study is to evaluate the safety and tolerability of 2 experimental drug combinations in people who have been diagnosed with an advanced/metastatic (cancer that has spread from where it started) solid ...


Pancreas

Ponsegromab in Adults With Cachexia and Metastatic Pancreatic Ductal Adenocarcinoma

This study focuses on adults who have cachexia (a condition that causes significant unintentional weight loss and muscle wasting) and newly diagnosed metastatic pancreatic cancer (cancer that has spread from the pancreas to other parts ...


Leukemia, not otherwise specified

Ziftomenib in Combination With Nonintensive or Intensive Therapy in Acute Myeloid Leukemia

This study focuses on people with acute myeloid leukemia (AML) and consists of 2 independent studies/ treatment regimens. AML is a type of blood cancer in which infection-fighting cells (white blood cells) do not mature ...


Breast

Shortened Duration of Adjuvant Therapy in Early-Stage HER2+ Breast Cancer

This study focuses on people who have been diagnosed with HER2-positive (HER2+) breast cancer and have recently completed chemotherapy in combination with a drug called trastuzumab, followed by breast surgery. The chemotherapy plus trastuzumab produced ...