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166 results found


Lung

HLX43 (Anti-PD-L1 ADC) in Advanced Non-Small Cell Lung Cancer

The purpose of this study is to determine the safety and effectiveness of an experimental drug called HLX43 for the treatment of advanced non-small cell lung cancer (NSCLC). Study procedures include administration of HLX43, questionnaires, ...


Breast, Cervix, Lung, Other Female Genital, Ovary

SNV4818 as Monotherapy or in Combination With Other Anticancer Agents

The purpose of this study is to evaluate different drug doses of an experimental drug called SNV4818 and identify safe levels in patients with an advanced cancer that has a mutation (change) in their PIK3CA ...


Anus, Colon, Lung, Pancreas, Rectum

BBO-11818 in Advanced KRAS Mutant Cancers

This study focuses on people who have advanced non-small cell lung cancer, colorectal cancer, pancreatic ductal adenocarcinoma, or other solid tumor with a specific KRAS mutation (change in the KRAS gene that plays a part ...


Prostate

Mevrometostat With Enzalutamide in Metastatic Castration-Sensitive Prostate Cancer

This study focuses on people who have metastatic castration-sensitive prostate cancer (mCSPC) and have not received treatment with novel hormonal therapy or chemotherapy in the mCSPC setting. The purpose of the study is to learn ...


Prostate

CCTG/NRG, CCTG-PR26, Ph 3, rand, prostate cancer, Docetaxel + androgen inhibitors

Primary Objective: To compare overall survival (OS) in participants with mCSPC who are receiving standard of care ADT (between 6-12 months exposure) + ARPI (>= 4-months exposure) and have suboptimal PSA response (PSA >=0.2 ng/ml at ...