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150 results found


Eye and Orbit, Liver, Melanoma

RP2 in Combination With Nivolumab Versus Ipilimumab in Combination With Nivolumab in Metastatic Uveal Melanoma

This study focuses on immune checkpoint inhibitor-naive adults with inoperable metastatic uveal melanoma (a type of aggressive eye cancer that has not been treated with immune checkpoint inhibitor therapies). The purpose of the study is ...


Leukemia, other

Venetoclax and HMA-based Therapies for Adults With FLT3-mutated Acute Myeloid Leukemia: A MyeloMATCH Treatment Trial

This study focuses on adults diagnosed with acute myeloid leukemia (AML) who have previously participated in another study called the myeloMATCH study. The purpose of this research is to compare the usual drug combination treatment ...


Esophagus, Stomach

Nivolumab + Paclitaxel + Ramucirumab in Advanced Gastric and Esophageal Adenocarcinoma

This study focuses on people who have advanced stomach or esophageal cancer that has spread. The purpose of the study is to compare the usual treatment alone (the combination of 2 drugs, paclitaxel and ramucirumab) ...


Breast, Colon, Esophagus, Kidney, Lip, Oral Cavity and Pharynx, Liver ...

Teva, TV56278-ONC-10203, Ph1a/1b, Open Label, Locally Adv or Metastatic Solid Tumors, TEV-56278

Objectives Primary To characterize the safety and tolerability of TEV-56278 in the trial population To determine a RP2D Secondary To characterize the serum pharmacokinetics of TEV-56278 in the trial population To evaluate the antitumor activity of ...


Breast, Cervix, Esophagus, Kidney, Liver, Lung, Melanoma, Other Female Genital ...

Phase 1/2 Study of CRB-601 in Patients With Advanced Solid Tumors

The purpose of this study is to determine whether an experimental drug called CRB-601 can help people with advanced solid tumors (cancer). The study aims to evaluate how well the drug is tolerated and identify ...