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156 results found


Lung

BNT324 with BNT327 in Participants With Advanced Lung Cancer

The purpose of this study is to assess whether the investigational drugs BNT324 and BNT327 can help control advanced or metastatic lung cancer. The study aims to determine the most suitable combination dose of BNT324 ...


Unknown Sites

VEGFR2/MET Inhibitor Cabozantinib in Combination With Cytotoxic Chemotherapy for Newly Diagnosed Osteosarcoma

This study focuses on individuals who have a type of bone cancer called osteosarcoma (OST). The purpose of the study is to evaluate how well an experimental drug called cabozantinib works in combination with methotrexate, ...


Urinary Bladder

Bladder Preservation with Immunoradiotherapy in Muscle Invasive Bladder Cancer

This study focuses on people who have responded to chemotherapy or chemotherapy-like treatment for muscle invasive bladder cancer, and the cancer has either shrunk or cannot be found. The purpose of the study is to ...


Lymphoid Leukemia, Non-Hodgkin's Lymphoma

Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid in Diffuse-Large B-Cell Lymphoma and High-Grade B-Cell Lymphoma

The purpose of this study is to determine whether treatment with ViPOR (a combination of the drugs venetoclax, ibrutinib, prednisone, obinutuzumab, and lenalidomide) will lead to disappearance of all sites of cancer (i.e., complete remission) ...


Brain and Nervous System

Single Fraction Stereotactic Radiosurgery Versus Fractionated SRS For Intact Brain Metastases

This study focuses on people who are having stereotactic radiosurgery (SRS) to treat cancer that has spread to their brain. The purpose of the study is to determine whether a type of SRS radiation treatment ...