Find Clinical Trials | Cedars-Sinai

162 results found

Anus, Breast, Lung, Other Female Genital, Ovary, Unknown Sites

Sumitomo Pharma America, Inc, SMP-3124-101, PhI/II, Open-label, SMP-3124LP, Solid tumors

Primary Objective: Dose Escalation: Determine the Recommended Phase 2 Dose (RP2D). Assess the safety and tolerability. Dose Expansion: Evaluate preliminary antitumor activity. Secondary Objectives: Dose Escalation: Establish the plasma PK profile of SMP-3124 and SMP-3124LP. Evaluate ...

Unknown Sites

BL-M07D1 in Subjects With HER2 Expressing Advanced Malignant Solid Tumors

The purpose of this study is to evaluate the safety, tolerability, and effectiveness of an experimental drug called BL-M07D1 as a possible treatment for people who have a type of advanced, inoperable cancer that expresses ...

Breast

Bria-IMT Regimen With Check Point Inhibitor vs Physician’s Choice in Metastatic Breast Cancer

The purpose of this study is to assess the safety and effectiveness of an experimental therapy for advanced breast cancer called Bria-IMT (SV-BR-1-GM) cancer vaccine in combination with immune checkpoint inhibitor retifanlimab. Retifanlimab can help ...

Lung

BNT324 with BNT327 in Participants With Advanced Lung Cancer

The purpose of this study is to assess whether the investigational drugs BNT324 and BNT327 can help control advanced or metastatic lung cancer. The study aims to determine the most suitable combination dose of BNT324 ...

Unknown Sites

VEGFR2/MET Inhibitor Cabozantinib in Combination With Cytotoxic Chemotherapy for Newly Diagnosed Osteosarcoma

This study focuses on individuals who have a type of bone cancer called osteosarcoma (OST). The purpose of the study is to evaluate how well an experimental drug called cabozantinib works in combination with methotrexate, ...