Find Clinical Trials | Cedars-Sinai

156 results found

Leukemia, not otherwise specified

Ziftomenib in Combination With Nonintensive or Intensive Therapy in Acute Myeloid Leukemia

This study focuses on people with acute myeloid leukemia (AML) and consists of 2 independent studies/ treatment regimens. AML is a type of blood cancer in which infection-fighting cells (white blood cells) do not mature ...

Breast

Shortened Duration of Adjuvant Therapy in Early-Stage HER2+ Breast Cancer

This study focuses on people who have been diagnosed with HER2-positive (HER2+) breast cancer and have recently completed chemotherapy in combination with a drug called trastuzumab, followed by breast surgery. The chemotherapy plus trastuzumab produced ...

Unknown Sites

AVZO-1418 in Locally Advanced or Metastatic Solid Tumors

The purpose of this study is to evaluate the safety and tolerability of an experimental drug called AVZO-1418 for the treatment of locally advanced solid tumors (cancers that have grown to a serious stage and ...

Breast, Colon, Esophagus, Kidney, Liver, Lung, Melanoma, Other Female Genital ...

Corcept Therapeutics, CORT125236-750, Ph 1b/2, Nenocorilant in Combo w Nivo, Adv Solid Malignancies

Dose-Finding Phase 1b - Part 1 Primary Objectives: To evaluate the safety and tolerability of nenocorilant in combination with nivolumab in patients with advanced solid malignancies. To determine the maximum tolerated dose (MTD) and/or the ...

Colon, Rectum

Summit Therapeutics, SMT112-3005, Ph3, rand, Ivonescimab+FOLFOX vs Bev+FOLFOX, CRC

Primary Objective: To compare the progression-free survival (PFS) as assessed by blinded Independent Radiological Review Committee (IRRC) based on Response Evaluation Criteria in Solid Tumors (RECIST) v1.1, of ivonescimab in combination with modified 5-FU, oxaliplatin, and leucovorin (mFOLFOX6) ...