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158 results found


Melanoma

Fianlimab, Cemiplimab, and Ipilimumab in Anti-PD-1 Refractory Melanoma

The purpose of this study is to determine whether the drug combination of fianlimab, cemiplimab, and ipilimumab is a safe and effective treatment for refractory melanoma. The study focuses on people whose melanoma has spread ...


Breast

Ivonescimab in Combination With Carboplatin + Docetaxel in Early Stage Triple Negative Breast Cancer

The purpose of this study is to evaluate the safety and effectiveness of an experimental drug called ivonescimab when combined with standard chemotherapy (carboplatin and docetaxel) before surgery for the treatment of early stage, triple-negative ...


Lymphoid Leukemia

P-CD19CD20-ALLO1 in Subjects with Selected Relapsed/Refractory B Cell Malignancies

This study focuses on people who have a B cell malignancy that has returned after responding to previous treatment (relapsed) or is not responding to treatment (refractory). The purpose of the study is to determine ...


Unknown Sites

Doxorubicin + Pembrolizumab Versus Doxorubicin Alone in Undifferentiated Pleomorphic Sarcoma and Related Poorly Differentiated Sarcomas

The purpose of this study is to determine whether adding an immunotherapy drug (pembrolizumab) to standard chemotherapy (doxorubicin) can help patients with certain types of sarcoma (cancer) live longer without having disease progression. Participants will ...


Pancreas

Physical Activity Using Digital Health Technology in Adults With Cachexia and Metastatic Pancreatic Ductal Adenocarcinoma

This study focuses on adults who have pancreatic cancer that has spread and caused unintentional weight loss. The purpose of the study is to evaluate whether a wearable device can be used to measure physical ...