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164 results found


Small Intestine, Stomach

DRX-42 Versus Sunitinib in Metastatic and/or Unresectable Gastrointestinal Stromal Tumors After Imatinib Therapy

The purpose of this study is to determine the safety and effectiveness of an experimental drug called IDRX-42 compared to a drug called sunitinib (standard-of-care treatment) in people who have been diagnosed with advanced gastrointestinal ...


Breast

Reinvigorating Response To Immunotherapy in Triple-Negative Breast Cancer With Combination Myeloid Inhibition and Radiation

The purpose of this study is to evaluate the safety and effectiveness of a drug called pembrolizumab in combination with radiation therapy and another drug, axatilimab, in the treatment of patients with metastatic or locally ...


Lymphoid Leukemia

Rondecabtagene Autoleucel Vs. CD19 CAR T Cell Therapy in Large B-Cell Lymphoma

The purpose of this study is to find new ways to treat lymphomas that have either come back after treatment or have stopped responding to treatment in patients who have aggressive B-cell non-Hodgkin lymphoma. The ...


Other Digestive Organ

Intraperitoneal Paclitaxel Plus Systemic Treatment Versus Systemic Treatment Alone in Gastric Carcinomatosis

This study focuses on people who have gastric cancer that has spread to the abdominal cavity. Researchers aim to determine whether they can lower the chance that the patient’s gastric cancer grows or spreads by ...


Anus, Bones and Joints, Brain and Nervous System, Breast, Cervix ...

S241656 as Monotherapy and in Combination With Other Anti-Cancer Therapies

The purpose of this study is to evaluate an experimental drug called S241656 in people who have cancer with a mutation in the KRAS, NRAS, HRAS, BRAF, and/or CRAF (RAF1) genes in their tumor. S241656 ...